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  1. Abnormal preconception thyrotropin levels were associated with fecundability and adverse fetomaternal outcomes, however, little is known regarding the natural change of serum thyrotropin in euthyroid preconce...

    Authors: Rili Gao, Xinyi Lyu, Ying Yang, Jinrong Fu, Chuanyu Zhao, Haixia Guan and Xu Ma
    Citation: Thyroid Research 2024 17:5
  2. Spindle epithelial tumor with thymic like elements (SETTLE) is a biphasic tumor composed of epithelial and spindle cell components. It is an uncommon indolent tumor arising in the thyroid gland and most common...

    Authors: Bangalore Rammohan Nagarjun, Shailee Mehta, Jahnavi Gandhi, Priti Trivedi and Priyank rathod
    Citation: Thyroid Research 2024 17:6
  3. Whether prophylactic central lymph node dissection is necessary for patients with clinically node-negative (cN0) papillary thyroid microcarcinoma (PTMC) remains controversial. Herein, we aimed to establish an ...

    Authors: Jie Liu, Jingchao Yu, Yanan Wei, Wei Li, Jinle Lu, Yating Chen and Meng Wang
    Citation: Thyroid Research 2024 17:4
  4. Coexistence of TSH-secreting pituitary adenoma (TSHoma) and Graves’ disease (GD) is rare and complicates the management decision.

    Authors: Adeel Ahmad Khan, Shahd I. Ibrahim, Fateen Ata, Bara Wazwaz, Mohammad Abdulalim Hanoun, Sirajeddin Belkhair, Zaina Seros Rohani and Zeinab Dabbous
    Citation: Thyroid Research 2024 17:3
  5. Thyroid storm is a state of circulating thyroid hormone excess leading to multiorgan dysfunction and systemic decompensation. It typically occurs in the setting of poorly controlled hyperthyroidism and a preci...

    Authors: Vidhu Vadini, Prabhav Vasistha, Almog Shalit and Spyridoula Maraka
    Citation: Thyroid Research 2024 17:2
  6. To describe the demographic characteristics and clinical outcomes following the first cohort of patients with Bening Thyroid Nodule (BTN) and (Papillary Thyroid Microcarcinoma) (PTMC) treated with Radiofrequen...

    Authors: Cristhian Garcia, Paola Solis-Pazmino, Eddy P. Lincango, Andrea S. Cho-Tana, Luis Figueroa, Oscar J. Ponce, Juan P. Brito and Erivelto Volpi
    Citation: Thyroid Research 2024 17:1
  7. Having to take levothyroxine (L-T4) on a daily basis, on an empty stomach is burdensome and may impair adherence, especially during Ramadan fasting. A long half-life and autoregulation of thyroid hormone level...

    Authors: Tamer Mohamed Elsherbiny
    Citation: Thyroid Research 2023 16:44
  8. Subclinical hypothyroidism is diagnosed when serum thyroid stimulating hormone levels are higher whilst free thyroxine levels remain within their respective reference ranges. These reference ranges are uniform...

    Authors: Mia Holley, Salman Razvi, Rosie Dew, Ian Maxwell and Scott Wilkes
    Citation: Thyroid Research 2023 16:43
  9. The zinc-finger CCHC-type (ZCCHC) superfamily proteins are characterized by the shared sequence CX2-CX4-HX4-C and thought to own high affinity to single-stranded nucleic acids, particularly RNAs. In humans, a ...

    Authors: Yin Yin, Jing Chen, Qian Chen, Hongyan He, Nannan Zhu, Pengcheng Xia, Chunli Yu and Lingyun Meng
    Citation: Thyroid Research 2023 16:42
  10. Goitre is commonly caused by a lack of iodine in the diet. This condition is particularly prevalent in high-altitude areas where iodine deficiency is common. Here we speculate that inorganic nitrate, the oxida...

    Authors: Jon O. Lundberg and Eddie Weitzberg
    Citation: Thyroid Research 2023 16:41
  11. Inconsistencies in the medical management of hypothyroidism have been reported between endocrinologists in different countries. This study aimed to identify the attitudes of Latin America thyroid specialists t...

    Authors: Jessica F. Cassemiro, Veronica Ilera, Stella Batalles, Adriana Reyes, Endre V. Nagy, Enrico Papini, Petros Perros, Laszlo Hegedüs and Helton Estrela Ramos
    Citation: Thyroid Research 2023 16:40
  12. Struma ovarii refers to rare mature cystic teratomas containing at least 50% of thyroid tissue, and malignant transformation is known to be even rarer. The synchronous development of malignant struma ovarii an...

    Authors: Maryam Kabootari, Reza Habibi Tirtashi, Azita Zadeh-Vakili, Maryam Zarkesh, Hossein Samadanifard, Shirin Haghighi, Fereidoun Azizi and Atieh Amouzegar
    Citation: Thyroid Research 2023 16:39
  13. Subclinical hypothyroidism in pregnancy and definition by upper thyrotropin (TSH) cutoff are controversial. As mitochondria are influenced by thyroid hormones, the purpose in this study was to measure expressi...

    Authors: Julie Kristine Guldberg Stryhn, Jacob Larsen, Palle Lyngsie Pedersen and Peter Haulund Gæde
    Citation: Thyroid Research 2023 16:38
  14. Evidence on the impact of thyroid hormone treatment (LT4) on maternal pregnancy outcomes in women with subclinical hypothyroidism (SCH) without thyroid peroxidase antibodies (TPOAb) positivity is scarce.

    Authors: Georgiana Sitoris, Flora Veltri, Emna Jelloul, Pierre Kleynen, Serge Rozenberg and Kris G. Poppe
    Citation: Thyroid Research 2023 16:29
  15. We investigated the association between health-related quality of life (HRQL) and the severity of hypothyroidism at diagnosis in patients referred to a secondary hospital clinic.

    Authors: Camilla B. Larsen, Kristian Hillert Winther, Per Karkov Cramon, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen, Mogens Groenvold, Jakob Bue Bjorner, Laszlo Hegedüs, Torquil Watt and Steen Joop Bonnema
    Citation: Thyroid Research 2023 16:37
  16. Ultrasonography is a noninvasive modality for the initial assessment of thyroid nodules. The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) has demonstrated good performa...

    Authors: Hamdi Mohamed Isse, Robert Lukande, Senai Goitom Sereke, Fualal Jane Odubu, Rita Nassanga and Samuel Bugeza
    Citation: Thyroid Research 2023 16:26
  17. Ultrasound is the first-line imaging modality for detection and classification of thyroid nodules. Certain features observable by ultrasound have recently been equated with potential malignancy. This retrospec...

    Authors: Michael Cordes, Theresa Ida Götz, Stephan Coerper, Torsten Kuwert and Christian Schmidkonz
    Citation: Thyroid Research 2023 16:25
  18. In Sudan, there is limited knowledge on the epidemiology, clinical characteristics and pathological patterns of thyroid cancer. To address this shortcoming, we studied the clinical, pathological and treatment ...

    Authors: Moawia Mohammed Ali Elhassan, Mohamed Dafalla Awadalla Gismalla, Sahar Abdelrahman Hamid Mohamed and Areeg Faggad
    Citation: Thyroid Research 2023 16:35
  19. Being critical for brain development and neurocognitive function thyroid hormones may have an effect on behaviour and brain structure. Our exploratory study aimed to delineate the influence of mutations in the...

    Authors: Berenike Rogge, Marcus Heldmann, Krishna Chatterjee, Carla Moran, Martin Göttlich, Jan Uter, Tobias A. Wagner-Altendorf, Julia Steinhardt, Georg Brabant, Thomas F. Münte and Anna Cirkel
    Citation: Thyroid Research 2023 16:34
  20. The literature considers sclerotherapy to be a safe and effective treatment for benign thyroid cysts. No subsequent diagnostic problems have been reported as a complication. We report the occurrence of focal i...

    Authors: Steven Raeymaeckers, Maurizio Tosi, Bastiaan Sol and Johan De Mey
    Citation: Thyroid Research 2023 16:33
  21. Lacrimal gland enlargement can be a feature of thyroid eye disease (TED). Unilateral or asymmetric lacrimal gland enlargement is poorly described and may impede diagnosis. We present the histological and clini...

    Authors: Pav Gounder, Huw Oliphant, Valerie Juniat, Michael Koenig, Dinesh Selva and Saul N. Rajak
    Citation: Thyroid Research 2023 16:32
  22. The discovery of driver oncogenes for thyroid carcinomas and the identification of genomically targeted therapies to inhibit those oncogenes have altered the treatment algorithm in thyroid cancer (TC), while g...

    Authors: Suzanne Murray, Vivek Subbiah, Steven I. Sherman, Sophie Péloquin, Anthony Sireci, Christian Grohé, Patrick Bubach and Patrice Lazure
    Citation: Thyroid Research 2023 16:22
  23. Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) are common differentiated thyroid cancers, but the detection of a collision tumor is an extremely rare event.

    Authors: Kanako Kawasaki, Keita Kai, Nariyuki Tanaka, Shinichi Kido, Arisa Ibi, Akimichi Minesaki, Moriyasu Yamauchi, Yuichiro Kuratomi, Shinichi Aishima, Masahiro Nakashima and Masahiro Ito
    Citation: Thyroid Research 2023 16:24
  24. The aim of this study was to evaluate macular blood flow in patients with thyroid-associated orbitopathy (TAO) as compared to healthy subjects. The inflammatory nature of the disease, as well as the vascular c...

    Authors: Mojtaba Abrishami, Aliakbar Sabermoghaddam, Zeinab Salahi, Elham Bakhtiari and Mehrdad Motamed Shariati
    Citation: Thyroid Research 2023 16:31
  25. The thyroid gland's neurovascular relationship is commonly portrayed as the recurrent laryngeal nerve (RLN) coursing posteriorly to the thyroid gland. We report a rare case with the RLN running anteriorly to a...

    Authors: Minoru Kihara, Akira Miyauchi, Makoto Fujishima, Tomo Ishizaka, Akihide Matsunaga, Shiori Kawano, Masashi Yamamoto, Takahiro Sasaki, Hiroo Masuoka, Takuya Higashiyama, Yasuhiro Ito, Naoyoshi Onoda, Akihiro Miya and Takashi Akamizu
    Citation: Thyroid Research 2023 16:30
  26. In the last decade, the combination of the widespread use of streptavidin–biotin technology and biotin–containing supplements (BCS) in the daily clinical practice, have led to numerous reports of erroneous hor...

    Authors: Nicholas Angelopoulos, Rodis D. Paparodis, Ioannis Androulakis, Panagiotis Anagnostis, Anastasios Boniakos, Leonidas Duntas, Spyridon N. Karras and Sarantis Livadas
    Citation: Thyroid Research 2023 16:18
  27. Thyroid hormones are of fundamental importance for brain function. While low triiodothyronine levels during acute ischemic stroke (AIS) are associated with worse clinical outcomes, dynamics of thyroid function...

    Authors: Evgeny Sidorov, Aruna Paul, Chao Xu, Claire Delpirou Nouh, Allshine Chen, Albina Gosmanova, Niyaz Gosmanov, David Lee Gordon, Irina Baranskaya, Juliane Chainakul, Robert Hamilton and Alexander Mdzinarishvili
    Citation: Thyroid Research 2023 16:28
  28. Thyroid cancer (TC) patients are understudied but appear to be at risk for poor physical and psychosocial outcomes. Knowledge of the course and determinants of these deteriorated outcomes is lacking. Furthermo...

    Authors: Floortje Mols, Dounya Schoormans, Romana Netea-Maier, Olga Husson, Sandra Beijer, Katrijn Van Deun, Wouter Zandee, Marleen Kars, Pleun C. M. Wouters van Poppel, Suat Simsek, Patrick van Battum, Jérôme M. H. Kisters, Jan Paul de Boer, Elske Massolt, Rachel van Leeuwaarde, Wilma Oranje…
    Citation: Thyroid Research 2023 16:23
  29. Papillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like nuclear grooving, nuclear clearing, and intra-nuclear inclusions. However...

    Authors: Basavaraj Rangalakshmi Ashwini, Chandran Nirmala, Muthuvelu Natarajan and Dayananda S Biligi
    Citation: Thyroid Research 2023 16:21
  30. Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare complication of hyperthyroidism characterized by thyrotoxicosis, hypokalemia, and paralysis. It is the most common form of acquired periodic paralysis...

    Authors: Hawa Nuradin Mohamed, Abdi Karim Ahmed Ghedi, Sevgi Ozturk, Mohamed Osman Omar Jeele and Ahmed Muhammad Bashir
    Citation: Thyroid Research 2023 16:14
  31. Leiomyosarcoma (LMS) is a soft tissue malignant tumor that has a predilection to the abdominopelvic and limb smooth muscles. LMS of the thyroid is exceptionally rare. Papillary thyroid cancer (PTC) is the most...

    Authors: Mohamed Asiri, Faisal Alsarrani, Abdullah Altasan, Faisal Alqahtani, Lujain Akram Ali, Majed Pharaon, Saad Alshehri and Awad Alshahrani
    Citation: Thyroid Research 2023 16:16
  32. One of the common causes of suboptimal control of thyroid stimulating hormone (TSH) in levothyroxine-treated hypothyroidism is coadministration of proton pump inhibitors (PPIs). Morning administration of panto...

    Authors: Avivar Awasthi, Partha Pratim Chakraborty, Neeti Agrawal, Anirban Sinha, Anuj Kumar Pandey and Animesh Maiti
    Citation: Thyroid Research 2023 16:15
  33. Thyrotoxic periodic paralysis (TPP) is a rare condition characterized by muscle paralysis, thyrotoxicosis, and hypokalemia. It presents with paralysis of both proximal and distal musculature in upper and lower...

    Authors: Arne Heydorn, Birgitte Bertelsen, Rúna Louise Mortansdóttir Nolsöe, Pia Eiken and Peter Lommer Kristensen
    Citation: Thyroid Research 2023 16:10
  34. Graves’ disease (GD) is the main cause of hyperthyroidism in women of the fertile age. In pregnant women, the disease should be carefully managed and controlled to prevent maternal and fetal complications. Obs...

    Authors: Nanna Maria Uldall Torp, Inge Bülow Pedersen, Allan Carlé, Jesper Scott Karmisholt, Eva Ebbehøj, Diana Grove-Laugesen, Thomas Heiberg Brix, Steen Joop Bonnema, Bieke F. Schrijvers, Birte Nygaard, Lena Bjergved Sigurd, Ulla Feldt-Rasmussen, Marianne Klose, Åse Krogh Rasmussen, Stig Andersen and Stine Linding Andersen
    Citation: Thyroid Research 2023 16:11
  35. Thyroid hormones are key determinants of health and well-being. Normal thyroid function is defined according to the standard 95% confidence interval of the disease-free population. Such standard laboratory ref...

    Authors: Peter N. Taylor, Andrew Lansdown, Justyna Witczak, Rahim Khan, Aled Rees, Colin M. Dayan and Onyebuchi Okosieme
    Citation: Thyroid Research 2023 16:7

    The Correction to this article has been published in Thyroid Research 2023 16:20

  36. Thyroid disease in pregnant women is a matter of clinical awareness, and current clinical guidelines recommend a risk-based screening strategy. This study aimed to evaluate current clinical practice regarding ...

    Authors: Line Cleman Hatting, Marie Østergaard Kristensen, Maja Hjelm Lundgaard, Anne Sørensen and Stine Linding Andersen
    Citation: Thyroid Research 2023 16:9
  37. We have recently witnessed a rapid increase in the incidence of differentiated thyroid carcinoma (DTC), particularly low and very low-risk papillary thyroid carcinoma. Simultaneously, the number of cancer-rela...

    Authors: Jolanta Krajewska, Aleksandra Kukulska, Konrad Samborski, Agnieszka Czarniecka and Barbara Jarzab
    Citation: Thyroid Research 2023 16:4
  38. Brown bears hibernate throughout half of the year as a survival strategy to reduce energy consumption during prolonged periods with scarcity of food and water. Thyroid hormones are the major endocrine regulato...

    Authors: Anne Mette Frøbert, Claus G. Nielsen, Malene Brohus, Jonas Kindberg, Ole Fröbert and Michael T. Overgaard
    Citation: Thyroid Research 2023 16:3
  39. The brain metastasis from differentiated thyroid carcinoma (DTC) is a rare condition and its prognosis is poor. The standard protocol for screening and treatment of patients with brain metastases from papillar...

    Authors: Le Ngoc Ha, Le Quoc Khanh, Ngo Thi Minh Hanh, Hyo Jung Seo and Mai Hong Son
    Citation: Thyroid Research 2023 16:1
  40. Treatment patterns and outcomes of Graves’ disease (GD) are variable around the world. However, studies on treatment outcomes of GD from the Asian populations are limited. We aimed to evaluate treatment outcom...

    Authors: Wasit Kanokwongnuwat, Nawarat Penpong and Chaninporn Sangsri
    Citation: Thyroid Research 2022 15:24

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