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Table 2 FT3 and FT4 levels, as well as their ratios, in patient groups according to age

From: The ratio of serum free triiodothyronine to free thyroxine in children: a retrospective database survey of healthy short individuals and patients with severe thyroid hypoplasia or central hypothyroidism

 

3–5 y

6–8 y

9–11 y

12–14 y

15–18 y

Total

Control (n = 129)

n

24

19

31

36

19

129

FT3

4.11 ± 0.56

4.29 ± 0.43α

4.14 ± 0.38

3.89 ± 0.50α

3.93 ± 0.56

4.06 ± 0.50

FT4

1.36 ± 0.14

1.38 ± 0.11

1.36 ± 0.14

1.33 ± 0.16

1.31 ± 0.10

1.35 ± 0.14

FT3/FT4

3.02 ± 0.38

3.12 ± 0.31

3.07 ± 0.38

2.95 ± 0.35

3.01 ± 0.50

3.03 ± 0.38

A/Hypoplasia (n = 22)

nb

14

20

22

21

24

101

FT3

4.15 ± 0.51

3.86 ± 0.42

3.91 ± 0.45

3.84 ± 0.60

3.52 ± 0.60

3.82 ± 0.55*

FT4

1.95 ± 0.20**

1.81 ± 0.31**

1.76 ± 0.26**

1.85 ± 0.59**

1.90 ± 0.69**

1.85 ± 0.47**

FT3/FT4

2.15 ± 0.25**

2.18 ± 0.30**

2.25 ± 0.39**

2.23 ± 0.34**

2.03 ± 0.30**

2.17 ± 0.33**

Central (n = 27)

nb

11

31

46

31

26

145

FT3

3.50 ± 0.48

3.49 ± 0.53**

3.51 ± 0.64**

3.63 ± 0.64

3.46 ± 0.54

3.52 ± 0.58**

FT4

1.24 ± 0.23

1.31 ± 0.17

1.43 ± 0.29

1.45 ± 0.30

1.49 ± 0.25

1.41 ± 0.27

FT3/FT4

2.94 ± 0.58

2.68 ± 0.51*

2.49 ± 0.37**

2.52 ± 0.37*

2.37 ± 0.40**

2.55 ± 0.45**

  1. Values are pg/mL (FT3) and ng/dL (FT4); mean ± standard deviation
  2. α P < 0.05, *P < 0.05; **P < 0.01, compared to control, respectively
  3. bIn A/Hypoplasia and Central, patients underwent repetitive measurements of FT3 and FT4. All the values are averaged according to the chronological age of the patients. The same patients may have average independent measurement values in more than one age category if they were evaluated over multiple years