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Table 5 Predictors of TSH normalization among hyperthyroid patients attending UoGCSH

From: Normalization of thyroid function tests among thyrotoxicosis patients attending a University Hospital in North-West Ethiopia

Variables

 

Univariate analysis

Multivariate analysis

CHR (95% CI)

p-value

AHR (95% CI)

p-value

Age (years)

 

0.987 [0.970–1.005]

0.151

0.967 [0.937–0.998]

0.036

Gender

Female

0.992 [0.359–2.379]

0.988

Etiology

GD

1

 

1

 

TMNG

0.343 [0.141–0.836]

0.019

0.580 [0.147–2.287]

0.436

Toxic nodular goiter

0.415 [0.166–1.038]

0.060

0.872 [0.218–3.499]

0.847

Duration of symptoms before treatment (months)

 

0.998 [0.996–1.000]

0.141

1.000 [0.997–1.002]

0.708

WHO goiter size

0

1

 

1

 

I

0.248 [0.030–2.024]

0.193

II

0.356 [0.047–2.676]

0.315

III

0.336 [0.042–2.692]

0.304

Baseline TSH

 

1.293 [0.891–1.874]

0.175

1.214 [0.647–2.279]

0.545

Baseline FT4

 

0.993 [0.990–0.996]

0.000

0.992 [0.988–0.997]

0.000

Baseline T3

 

0.907 [0.797–1.033]

0.142

0.966 [0.887–1.051]

0.418

PTU dose: initial

 

1.001 [0.999–1.004]

0.246

1.001 [0.999–1.004]

0.289

PTU dose: Maintenance

 

0.999 [0.995–1.004]

0.832

0.999 [0.994–1.004]

0.662

  1. AHR Adjusted Hazard Ratio, CHR Crude Hazard Ratio, CI Confidence Interval, GD Grave’s Disease, FT4 Free Thyroxine, PTU Propylthiouracil, T3 Triiodo thyronine, TMNG Toxic Multinodular Goiter, TFT Thyroid Function Tests, TSH Thyroid Stimulating Hormone, WHO World Health Organization