Table 1 Some clinical data on the groups of subjects studied. Median and 25th and 75th percentile values are reported in brackets

Age (years)

41.2 ± 7.5 (43; 37–47)

42.4 ± 9.2 (45; 40–49)

33.1 ± 10.1 (33; 24–42)

< 0.0001; a

Mother’s age on menopause (years)

51.0 ± 4.2 (51; 50–54)

51.1 ± 4.2 (51; 49–55)

50.1 ± 4.2 (51; 48–52)

0.57

Time since primary treatments (years)

7.2 ± 6.8 (5: 2–9)

4.6 ± 4.1 (3; 1–7)

n.a.

0.07

BMI (kg/m2)

25.3 ± 6.0 (23.5; 21.6–27.0)

24.2 ± 6.0 (23.5; 21.6–27.0)

24.5 ± 6.5 (23.8; 21.0–25.3)

0.45

Cumulative RAI activity (mCi)

100.1 ± 117.4 (80; 60–100)

n.a.

n.a.

–

Cured (%) / Biochemical disease (%)

97/3

100/0

n.a.

0.55

L-T4 dosage (μg/week)

859.1 ± 157.3 (825; 775–925)

741.3 ± 148.4 (725; 644–875)

n.a.

0.001

TSH (mIU/l)

0.46 ± 0.83 (0.17; 0.04–0.42)

1.69 ± 1.78 (1.37; 0.25–2.31)

2.35 ± 1.79 (2.11; 1.23–2.81)

< 0.0001; b, c

f-T4 (pmol/l)

20.5 ± 4.9 (20.7; 18.1–23.2)

16.5 ± 3.9 (16.4; 15.2–19.0)

13.8 ± 3.3 (13.4; 11.4–16.7)

< 0.0001; d, e, f

Tg (μg/l)

0.24 ± 0.47 (0.20; 0.04–0.20)

1.32 ± 3.20 (0.20; 0.09–0.67)

n.d.

0.01

TgAb positive (%)

2

4

n.d.

0.17