Fig. 1From: The interrelationship between pregnancy, venous thromboembolism, and thyroid disease: a hypothesis-generating reviewA simplified overview of the secondary hemostasis including the main alterations in pregnancy. Factors that considerably change in pregnancy are marked in bold (protein S (PS) decreases, others increase), and anticoagulants are marked in italic. See text for details. AT; antithrombin, PAI-1; plasminogen activator inhibitor-1, PAI-2: plasminogen activator inhibitor-2, PCa; activated protein C, TF: tissue factor, TFPI; tissue factor pathway inhibitor, t-PA; tissue-type plasminogen activatorBack to article page