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Table 2 The relationship between permanent congenital hypothyroidism (CH) and potential risk factors

From: Risk factors for transient and permanent congenital hypothyroidism: a population-based case-control study

Variables Control
N = 340
Permanent CH
N = 136
OR (95% CI) P value*
Parental consanguineous marriage
 No 296 (87.1) 106 (77.9) 1 1
 Yes 44 (12.9) 30 (22.1) 2.31 (1.6–3.3) 0.001
Betadine usage
 No 336 (98.8) 130 (95.5) 1 1
 Yes 4 (1.2) 6 (4.4) 3.8 (1.07–13.8) 0.039
Sex
 Boy 181 (53.2) 74 (54.4) 1 1
 Girl 159 (46.8) 62 (56.6) 0.95 (0.64–1.42) 0.81
History of CH in the first degree family
 No 335 (98.5) 121 (89) 1 1
 Yes 5 (1.5) 15 (11) 8.25 (2.93–23.2) 0.001
Neonatal jaundice
 No 299 (87.9) 84 (61.8) 1 1
 Yes 41 (12.1) 52 (38.2) 4.5 (2.8–7.26) 0.001
Birth weight (gr)
  < 2500 19 (5.6) 21 (15.4) 1 1
 4000–2500 308 (90.6) 110 (80.9) 0.29 (0.14–0.56) 0.01
  > 2500 13 (93.8) 5 (3.7) 0.31 (0.09–1.04) 0.059
Mother’s age (year)
  < 20 43 (12.6) 24 (17.6) 1 1
 20–30 97 (28.5) 48 (35.3) 1.6 (0.89–3.5) 0.1
 30–40 127 (37.4) 41 (30.1) 1 (0.89–2.94) 0.11
  > 40 73 (21.5) 23 (16.9) 0.31 (0.57–1.8) 0.93
  1. *Chi-square test was used in the all tests