Thyroid Research

Table 3 Patient parameters of cured (euthyroid and hypothyroid) and not cured patients for Graves’ disease, toxic multinodular goitre and solitary toxic adenoma. p-values of t-test is displayed

From: Radioiodine treatment outcome by dosimetric parameters and renal function in hyperthyroidism

		Graves’ disease		Toxic multinodular goitre		Solitary toxic adenoma
Parameter	Outcome	Mean	p	Mean	p	Mean	p
Age [years]	Cured	55	0.28	70	0.04	63	0.68
Age [years]	Not cured	53	0.28	72	0.04	66	0.68
24 h uptake [%]	Cured	53	< 0.01*	32	0.14	32	0.70
24 h uptake [%]	Not cured	60	< 0.01*	37	0.14	29	0.70
Mass [g]	Cured	49	< 0.01	46	0.64	26	0.48
Mass [g]	Not cured	54	< 0.01	50	0.64	45	0.48
Abs. dose [Gy]	Cured	122	0.38	162	0.45	266	0.32
Abs. dose [Gy]	Not cured	123	0.38	152	0.45	192	0.32
Activity [MBq]	Cured	477	0.01	764	0.01	757	0.80
Activity [MBq]	Not cured	434	0.01	630	0.01	737	0.80
Eff. half-life [d]	Cured	6.0	< 0.01*	6.8	0.81	6.2	-
Eff. half-life [d]	Not cured	6.5	< 0.01*	6.5	0.81	§	-
eGFR [ml/min/1.7m²]	Cured	78	0.34	70	0.02	74	-
eGFR [ml/min/1.7m²]	Not cured	80	0.34	57	0.02	§	-
Pre-treatment TSH (mU/l)	Cured	0.89	0.06	0.16	0.24	0.07	0.39
Pre-treatment TSH (mU/l)	Not cured	0.49	0.06	0.10	0.24	0.12	0.39

^§No eGFR-data was available due to small number of patients
^*Significant (p < 0.01) in multivariate logistic regression model

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