Table 1 Longitudinal studies of thyroid function in children and adolescents
Author and year | Cohort, number | Ages sampled | Assay Used | TSH change | FT4 change | FT3 change |
|---|---|---|---|---|---|---|
Taylor, 2017 [32] | ALSPACUK, n = 884 | 7, 15 yrs | Cobas e601 (Roche) | 7 to 15 yrs Increased by 0.12 mIU/L. No sex difference in change. | 7 to 15 yrs Decreased by 0.16 pmol/L. No sex difference in change. | 7 to 15 yrs Decreased by 0.48 pmol/L. Greater decline in girls than boys. |
Campbell, 2020 [42] | BLTS Australia, n = 1499 | 12, 14, 16 yrs | Abbott ARCHITECT | 12 to 14 yrs Boys: no change. Girls: no change. | 12 to 14 yrs Boys: no change. Girls: increased by 0.30 pmol/L. | 12 to 14 yrs Boys: Increased by 0.29 pmol/L Girls: Increased by 0.07 pmol/L |
14 to 16 yrs Boys: increased by 7.2%. Girls: increased by 4.9%. | 14 to 16 yrs Boys: increased by 0.64 pmol/L. Girls: increased by 0.42 pmol/L. | 14 to 16 yrs Boys: decreased by 0.62 pmol/L. Girls: decreased by 0.53 pmol/L. |