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Table 1 Case reports describing colorectal cancer metastases in thyroid gland since 2013

From: Colorectal cancer metastases in thyroid: case report and literature review

Author, Year

Age (y), Sex (M/F)

Cancer Origin

Primary Cancer TX

Time (y)

Studies

Thyroid Met TX

Other Metastatic Sites

Ozawa et al., 2015 [6]

72, F

Rectum

Anterior Resection

4

US, FNA, PET

ST

Lung, Adrenal

Roloff et al., 2016 [7]

42, F

Caecum

R hemicolectomy, adjuvant chemotherapy

2

US, FNA

TT

Liver, Lung

Mennet et al., 2016 [4]

68, M

Sigmoid

Sigmoid colectomy, adjuvant chemotherapy

2

PET, FNA – negative

L PT, TT & LND

Iliac-parietal nodules, Recto-vesical pouch

Minami et al., 2016 [8]

61, F

Sigmoid

Sigmoid colectomy

5

US, FNA -?PTC

TT & LND

Lung, Liver

Nicosia et al., 2016 [9]

75, M

Sigmoid

Sigmoid colectomy

6

PET, US, FNA

R PT

Lung

Coelho et al., 2017 [10]

64, F

Sigmoid

Sigmoid Colectomy, adjuvant chemotherapy

6

PET, US, FNA

R PT & LND

Lung, Liver, Pleura, Pericardium, Peritoneum

Dong-il et al., 2018 [11]

50, M

Descending colon

L hemicolectomy, adjuvant chemotherapy

4

PET

R PT & selective LND

Para-aortic nodes, Cervical nodes

Scepanovic et al., 2020 [12]

71, M

Rectum

Abdominoperineal resection, adjuvant chemotherapy

4

CT neck, FNA

TT

Lung

Zafar et al., 2020 [13]

57, F

Ascending Colon

R hemicolectomy, adjuvant chemotherapy

5

PET, US, FNA -? PTC

TT & LND

Lung

Mori et al., 2020 [14]

45, F

Rectum

Low Anterior Resection

5

CT, PET, US, FNA -Non-Diag

R PT & LND

Lung

Rojo-Abecia et al., 2020 [15]

85, F

Caecum

R hemicolectomy

14

PET, FNA

R PT

Lung

Hernandez et al., 2020 [5]

50, F

Rectum

Neo-adjuvant chemo-radiotherapy, anterior resection & total mesorectal excision

3.5

US, CT, FNA -? PTC

TT & LND

Lung

Momin et al., 2022 [16]

62, F

Caecum

R hemicolectomy

6

US, FNA, MRI neck, PET

R PT

Lung

Liver

Mardani et al., 2022 [17]

55, F

Descending colon

L hemicolectomy, adjuvant chemo-radiotherapy

8

PET, FNA -? PTC

TT & LND

Lung

  1. Abbreviations: Time The number of years to develop thyroid metastases after initial diagnosis of colorectal cancer, y Years, Studies Investigations and diagnostic studies done to evaluate thyroid metastases, Met Metastases, TX Treatment/management; US Ultrasonography, FNA Fine needle aspiration, PET Positron emission tomography, PTC Papillary thyroid carcinoma, CT Computed tomography, MRI Magnetic resonance imaging, ST Subtotal thyroidectomy, TT Total thyroidectomy, L Left, R Right, PT Partial thyroidectomy, & And, LND Lymph node dissection, Non-Diag Non-diagnostic,? Questionable