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Table 3 Changes in TSH concentration in both the groups with relation to timing of pantoprazole intake

From: Effect of morning versus night-time administration of proton pump inhibitor (pantoprazole) on thyroid function test in levothyroxine-treated primary hypothyroidism: a prospective cross-over study

Groups

TSH2-TSH1

TSH3-TSH2

TSH3-TSH1

p

 

Mean (± SD)

Mean (± SD)

Mean (± SD)

 

Study population (n = 30)

1.09 ± 3.33

0.69 ± 4.96

1.78 ± 4.05

 

Group M (n = 13)

1.07 ± 3.89

-0.01 ± 4.08

1.06 ± 3.09

0.61*

Group N (n = 17)

1.10 ± 1.70

1.22 ± 3.93

2.33 ± 3.21

0.91*

p

0.98**

0.40**

0.36**

 
  1. * Paired t-test between TSH2-TSH1 and TSH3-TSH2 in Group M and Group N
  2. ** Unpaired t-test between Group M and Group N for TSH2-TSH1, TSH3-TSH2 and TSH3-TSH1
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Thyroid Research

ISSN: 1756-6614