Table 1 Peak voxel coordinates
From: Changes in brain structure in subjects with resistance to thyroid hormone due to THRB mutations
A) FA maps control > RTHβ | ||||||
location | hemisphere | cluster Size | peak t-value | x | y | z |
corticospinal tract | left | 567 | 6.07 | 110 | 124 | 99 |
corticospinal tract | right | 275 | 4.31 | 145 | 137 | 108 |
4.08 | 139 | 134 | 101 | |||
B) Cortical Thickness | ||||||
location | hemisphere | cluster Size | peak t-value | x | y | z |
superior parietal cortex | left | 720 | 4.29 | 18 | -89 | 25 |
superior parietal cortex | right | 633 | 4.15 | -27 | -90 | 32 |
-20 | -87 | 26 | ||||
C) Voxel based morphometry | ||||||
location | hemisphere | cluster Size | peak t-value | x | y | z |
control > RTHβ | ||||||
inferior temporal | left | 162 | 4.08 | -50 | -12 | -28 |
front sup orb | right | 337 | 4.04 | 21 | 32 | -14 |
inferior temporal | right | 174 | 3.80 | 57 | -6 | -40 |
thalamus | left | 94 | 3.58 | -6 | -15 | -2 |
thalamus | right | 3.50 | 6 | -16 | -2 | |
RTHβ > control | ||||||
precuneus | left | 247 | 4.65 | -8 | -45 | 78 |
frontal mid | right | 275 | 4.42 | 51 | 34 | 34 |