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  1. The main subjects of discussion, held online within the ETA-CRN board invited 16 expert-panelists are shown. The ad hoc emerged ETA-CRN panel of experts (EPE) first congratulated Professor Kloos and the ATA Ta...

    Authors: Barbara Jarząb, Aleksandra Król, Kornelia Hasse-Lazar and Beata Jurecka-Lubieniecka

    Citation: Thyroid Research 2013 6(Suppl 1):S11

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 1

  2. In the 9th ETA-CRN Meeting (September 2009, Lisbon) some recommendations from the American Thyroid Association (ATA) guidelines for the management of medullary thyroid cancer (MTC) were discussed by an European P...

    Authors: Laura Fugazzola, Simone De Leo and Michela Perrino

    Citation: Thyroid Research 2013 6(Suppl 1):S8

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 1

  4. One of the most discussed and controversial issue in the management of thyroid nodules is the need to perform a routine measurement of serum Calcitonin (Ct) in all cases. The American Thyroid Association guide...

    Authors: Rossella Elisei and Cristina Romei

    Citation: Thyroid Research 2013 6(Suppl 1):S2

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 1

  6. Managing thyroid dysfunction is simple at first glance, the idea is to bring hormone levels in the euthyroid range, treat with antithyroid drugs, radio-iodine or surgery if toxic and replace with thyroxine or ...

    Authors: Durr e Sabih and Mohammad Inayatullah

    Citation: Thyroid Research 2013 6:2

    Content type: Review

    Published on:

  7. The article presents a case of 57-year-old woman with the infiltration of rare small lymphocytic B cell lymphoma in the thyroid gland. Initially, the patient was followed-up due to chronic lymphocytic B-cell l...

    Authors: Elżbieta Andrysiak-Mamos, Rafał Becht, Elżbieta Sowińska-Przepiera, Jakub Pobłocki, Justyna Syrenicz, Barbara Zdziarska, Katarzyna Karpińska-Kaczmarczyk and Anhelli Syrenicz

    Citation: Thyroid Research 2013 6:1

    Content type: Case report

    Published on:

  8. Recent findings in the past two decades have brought many insights into the biology of thyroid benign and malignant lesions, in particular the papillary and follicular thyroid cancers. Although, much progress ...

    Authors: Bartosz Pula, Pawel Domoslawski, Marzena Podhorska-Okolow and Piotr Dziegiel

    Citation: Thyroid Research 2012 5:26

    Content type: Review

    Published on:

  10. The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consis...

    Authors: Małgorzata Karbownik-Lewińska, Jan Stępniak and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:24

    Content type: Research

    Published on:

  11. In 1997 a currently obligatory model of iodine prophylaxis, based on mandatory iodization of household salt with 30 mg KI/kg, was introduced. The aim of our study was to assess the iodine intake among school-a...

    Authors: Arkadiusz Zygmunt, Zbigniew Adamczewski, Katarzyna Wojciechowska-Durczyńska, Anna Cyniak-Magierska, Kinga Krawczyk-Rusiecka, Agnieszka Zygmunt, Małgorzata Karbownik-Lewińska and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:23

    Content type: Research

    Published on:

  12. The risk of neoplastic transformation in patients with chronic thyroiditis (Hashimoto’s thyroiditis – HT) is slightly increased. Genetic background of this observation is still unclear. PI3K isoforms are linke...

    Authors: Katarzyna Wojciechowska-Durczynska, Kinga Krawczyk-Rusiecka, Anna Cyniak-Magierska, Arkadiusz Zygmunt, Stanisław Sporny and Andrzej Lewinski

    Citation: Thyroid Research 2012 5:22

    Content type: Research

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  13. Nowadays, the increasing number of oncologic patients with liver or pancreatic tumours are subjected to surgical treatment, as it can provide a long-term survival or sometimes cure. As a result, numerous new c...

    Authors: Katarzyna Wojciechowska-Durczynska, Arkadiusz Zygmunt, Adam Durczynski, Janusz Strzelczyk and Andrzej Lewinski

    Citation: Thyroid Research 2012 5:21

    Content type: Research

    Published on:

  14. The so called “big-big” prolactin (Prl), also known as macroprolactin is formed by Prl-immunoglobulin (Prl-IgG) complexes and may cause elevation of serum Prl concentrations measured by standard assays, potent...

    Authors: Krzysztof C Lewandowski, Danuta Gąsior-Perczak, Aldona Kowalska and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:20

    Content type: Short report

    Published on:

  16. Dendritic cells (DCs) play a major role as regulators of inflammatory events associated with thyroid pathology. The immunoregulatory function of DCs depends strongly on their subtype, as well as maturation and...

    Authors: Mariusz Stasiołek, Zbigniew Adamczewski, Bartosz Puła, Kinga Krawczyk-Rusiecka, Arkadiusz Zygmunt, Magdalena Borowiecka, Piotr Dzięgiel and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:18

    Content type: Research

    Published on:

  18. The endocrine system and particular endocrine organs, including the thyroid, undergo important functional changes during aging. The prevalence of thyroid disorders increases with age and numerous morphological...

    Authors: Adam Gesing, Andrzej Lewiński and Małgorzata Karbownik-Lewińska

    Citation: Thyroid Research 2012 5:16

    Content type: Review

    Published on:

  20. Sclerostin, a product of a SOST gene, is a protein expressed by osteocytes that inhibits osteoblastic bone formation. Several hormones, including PTH and glucocorticosteroids, have been suggested to be possible r...

    Authors: Elżbieta Skowrońska-Jóźwiak, Kinga Krawczyk-Rusiecka, Krzysztof C Lewandowski, Zbigniew Adamczewski and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:14

    Content type: Short report

    Published on:

  21. Recent attention has been given to subclinical hypothyroidism, defined as an elevation of TSH (4.5-10 uIU/L) with T4 and T3 levels still within the normal range. Controversy exists about the proper lower limit...

    Authors: Kimberly N Walter, Elizabeth J Corwin, Jan Ulbrecht, Laurence M Demers, Jeanette M Bennett, Courtney A Whetzel and Laura Cousino Klein

    Citation: Thyroid Research 2012 5:13

    Content type: Research

    Published on:

  22. Matrix metalloproteinases (MMPs), together with their tissue inhibitors (TIMPs), remodel extracellular matrix under physiological and pathological conditions and are implicated in pathogenesis of cardiovascula...

    Authors: A Lewiński, A Brona, KC Lewandowski, E Skowrońska-Jóźwiak and A Milewicz

    Citation: Thyroid Research 2012 5:12

    Content type: Research

    Published on:

  23. A 59-year old female patient presented with apathy and 6 kg weight gain. Investigations revealed severe primary hypothyroidism (TSH>100 μIU/ml). L-thyroxine (L-T4) was started and titrated up to 75 μg, once daily...

    Authors: Krzysztof C Lewandowski, Katarzyna Dąbrowska and Andrzej Lewiński

    Citation: Thyroid Research 2012 5:11

    Content type: Case report

    Published on:

  24. Considerable progress was made by the introduction of interferon to the treatment of chronic hepatitis C virus infection. This treatment, however, is associated with the risk of developing or exacerbating auto...

    Authors: Janina Krupińska, Waldemar Urbanowicz, Mariusz Kaczmarczyk, Grzegorz Kulig, Elżbieta Sowińska-Przepiera, Elżbieta Andrysiak-Mamos and Anhelli Syrenicz

    Citation: Thyroid Research 2012 5:10

    Content type: Research

    Published on:

  25. Thyroidectomy is a common surgical procedure, after which drains are placed routinely. This study aims to assess the benefits of placing postoperative drains, its complications and affects on postoperative sta...

    Authors: Zahid Ali Memon, Gulrayz Ahmed, Sarah Rafi Khan, Mahvesh Khalid and Naheed Sultan

    Citation: Thyroid Research 2012 5:9

    Content type: Research

    Published on:

  27. Altered somatotrophic signaling is among the most important potential mechanisms of extended longevity. Ames dwarf (df/df) mice are homozygous for mutation at the Prop-1 gene, leading to a lack of growth hormo...

    Authors: Adam Gesing, Andrzej Bartke, Michal M Masternak, Andrzej Lewiński and Małgorzata Karbownik-Lewińska

    Citation: Thyroid Research 2012 5:7

    Content type: Research

    Published on:

  28. Thyroid storm is an endocrinological emergency caused by an exacerbation of the hyperthyroid state and is characterized by multi organ dysfunction. Liver dysfunction or injury predominantly of a cholestatic ty...

    Authors: Davis Kibirige, Daniel Sekikubo Kiggundu, Richard Sanya and Edrisa Mutebi

    Citation: Thyroid Research 2012 5:6

    Content type: Case report

    Published on:

  29. Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism....

    Authors: Jonathan D Boyd and Ridas Juskevicius

    Citation: Thyroid Research 2012 5:5

    Content type: Case report

    Published on:

  30. Ophthalmopathy is a common manifestation of Graves’ disease (GD) occurring in up to 50% of patients. Mild eye signs are also common in patients with Hashimoto’s thyroiditis. Whilst a genetic predisposition to ...

    Authors: Melissa Ardley, Thomas McCorquodale, Hooshang Lahooti, Bernard Champion and Jack R Wall

    Citation: Thyroid Research 2012 5:4

    Content type: Research

    Published on:

  31. Thyroglobulin is a large protein present in all vertebrates. It is synthesized in the thyrocytes and exported to lumen of the thyroid follicle, where its tyrosine residues are iodinated . The iodinated thyrogl...

    Authors: Abdelaziz Belkadi, Caroline Jacques, Frédérique Savagner and Yves Malthièry

    Citation: Thyroid Research 2012 5:3

    Content type: Research

    Published on:

  33. Similar to other systems, the endocrine system is affected by aging. Thyroid hormone, the action of which is affected by many factors, has been shown to be associated with longevity. The most useful marker for...

    Authors: Satoru Suzuki, Shin-ichi Nishio, Teiji Takeda and Mitsuhisa Komatsu

    Citation: Thyroid Research 2012 5:1

    Content type: Research

    Published on:

  34. We report two patients with anorexia nervosa and Graves' disease who received subtotal thyroidectomy for Graves' disease and concomitantly experienced remission from anorexia nervosa. Both were young women (ag...

    Authors: Hitoshi Noguchi, Tsukasa Murakami, Shinya Uchino, Hiroto Yamashita and Shiro Noguchi

    Citation: Thyroid Research 2011 4:17

    Content type: Case report

    Published on:

  38. In recent few years is underlined that altered balance of pro- and anti-inflammatory cytokines play an important role in the pathogenesis of AITD.

    Authors: Artur Bossowski, Jerzy Harasymczuk, Anna Moniuszko, Anna Bossowska, Maciej Hilczer and Karol Ratomski

    Citation: Thyroid Research 2011 4:13

    Content type: Research

    Published on:

  39. Thyroid hormones are of crucial importance for the functioning of nearly every organ. Remarkably, disturbances of thyroid hormone synthesis and function are among the most common endocrine disorders affecting ...

    Authors: Klaudia Brix, Dagmar Führer and Heike Biebermann

    Citation: Thyroid Research 2011 4(Suppl 1):S9

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  40. Constitutively activating germline mutations in the thyrotropin receptor (TSHR) gene result in non-autoimmune hyperthyroidism and can be transmitted as a dominant trait or occur sporadically. These mutations a...

    Authors: Heike Biebermann, Franziska Winkler, Daniela Handke, Annette Grüters, Heiko Krude and Gunnar Kleinau

    Citation: Thyroid Research 2011 4(Suppl 1):S8

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  41. Thyroid hormones (TH) are essential for the development of the human brain, growth and cellular metabolism. Investigation of TH transporters became one of the emerging fields in thyroid research after the disc...

    Authors: Anita Kinne, Ralf Schülein and Gerd Krause

    Citation: Thyroid Research 2011 4(Suppl 1):S7

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  42. Thyroid hormone (TH) is essential for normal development, growth and metabolism. Its effects were thought to be principally mediated through triiodothyronine (T3), acting as a ligand for the nuclear TH recepto...

    Authors: Lars C Moeller and Martina Broecker-Preuss

    Citation: Thyroid Research 2011 4(Suppl 1):S6

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  43. RNA-binding proteins may regulate every aspect of RNA metabolism, including pre-mRNA splicing, mRNA trafficking, stability and translation of many genes. The dynamic association of these proteins with RNA defi...

    Authors: Bogusz Trojanowicz, Henning Dralle and Cuong Hoang-Vu

    Citation: Thyroid Research 2011 4(Suppl 1):S5

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  44. The monocarboxylate transporter 8 (MCT8) is a member of the major facilitator superfamily (MFS) and transports specificly iodothyronines. MCT8 mutations are the underlying cause of a syndrome of severe X-linke...

    Authors: Gunnar Kleinau, Ulrich Schweizer, Anita Kinne, Josef Köhrle, Annette Grüters, Heiko Krude and Heike Biebermann

    Citation: Thyroid Research 2011 4(Suppl 1):S4

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  45. Thyroid hormones play a critical role in brain development but also in the adult human brain by modulating metabolic activity. Hypothyroid states are associated with both functional and structural brain altera...

    Authors: Maximilian Pilhatsch, Michael Marxen, Christine Winter, Michael N Smolka and Michael Bauer

    Citation: Thyroid Research 2011 4(Suppl 1):S3

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  46. The cysteine peptidase cathepsin B is important in thyroid physiology by being involved in prohormone processing initiated in the follicle lumen and completed in endo-lysosomal compartments. However, cathepsin...

    Authors: Sofia Tedelind, Silvia Jordans, Henrike Resemann, Galia Blum, Matthew Bogyo, Dagmar Führer and Klaudia Brix

    Citation: Thyroid Research 2011 4(Suppl 1):S2

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  47. Thyroid cancer is one of the most common malignancies of the endocrine system with increasing incidence. The vast majority of thyroid carcinomas derive from thyroid hormone producing follicular cells. Carcinom...

    Authors: Juliane Braun and Stefan Hüttelmaier

    Citation: Thyroid Research 2011 4(Suppl 1):S1

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  49. Papillary thyroid cancer (PTC) comprises the commonest type of thyroid cancer and carries the highest rate of survival. However, when metastatic disease occurs, survival is significantly affected.

    Authors: Alexandra Chrisoulidou, Maria Boudina, Athanasios Tzemailas, Eleni Doumala, Pashalia K Iliadou, Frideriki Patakiouta and Kalliopi Pazaitou-Panayiotou

    Citation: Thyroid Research 2011 4:12

    Content type: Research

    Published on:

  50. Currently the cytological examination of fine needle aspiration (FNA) biopsies is the standard technique for the pre-operative differential diagnosis of thyroid nodules. However, the results may be non-informa...

    Authors: Kristine Ducena, Arturs Ābols, Janis Vilmanis, Zenons Narbuts, Juris Tārs, Diana Andrējeva, Aija Linē and Valdis Pīrāgs

    Citation: Thyroid Research 2011 4:11

    Content type: Research

    Published on:

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ISSN: 1756-6614