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  1. The cyclooxygenases are a group of enzymes catalyzing the formation of prostaglandins from arachidonic acid. Cyclooxygenase-1 (COX-1) is a constitutive form, thought to be a “housekeeping gene”, with constant ...

    Authors: Kinga Krawczyk-Rusiecka, Katarzyna Wojciechowska-Durczynska, Anna Cyniak-Magierska, Arkadiusz Zygmunt and Andrzej Lewinski
    Citation: Thyroid Research 2014 7:10
  2. The cell-mediated immune process by CD4+ and CD8+ lymphocyte subsets of T-cells has a major role in the pathogenesis of Hashimoto’s thyroiditis (HT). However, the exact mechanisms of initiation and progression...

    Authors: Teslime Ayaz, Serap Baydur Sahin, Osman Zikrullah Sahin, Medine Cumhur Cure, Fatih Sumer and Kadir Ilkkilic
    Citation: Thyroid Research 2014 7:11
  3. The pre-surgical selection of thyroid nodules with indeterminate cytology (Thy 3 according to British Thyroid Association) after fine-needle aspiration biopsy (FNAB) is currently required in order to reduce un...

    Authors: Massimo Giusti, Claudia Campomenosi, Stefano Gay, Barbara Massa, Enzo Silvestri, Eleonora Monti and Giovanni Turtulici
    Citation: Thyroid Research 2014 7:9
  4. Preoperative diagnostic investigations of nodular goiter are based on two main examinations: ultrasonography of the thyroid gland and ultrasound-guided fine-needle aspiration biopsy. So far, FNAB has been the ...

    Authors: Anhelli Syrenicz, Monika Koziołek, Andrzej Ciechanowicz, Anna Sieradzka, Agnieszka Bińczak-Kuleta and Miłosz Parczewski
    Citation: Thyroid Research 2014 7:6
  5. Whereas oxidative reactions occur in all tissues and organs, the thyroid constitutes such an organ, in which oxidative processes are indispensable for physiological functions. In turn, numerous metabolic react...

    Authors: Agnieszka Kokoszko-Bilska, Jan Stepniak, Andrzej Lewinski and Malgorzata Karbownik-Lewinska
    Citation: Thyroid Research 2014 7:5
  6. It is now recognized that TSH can act on targets other than the thyroid, including the liver. Elevated serum TSH levels in euthyroid subjects were recently reported to correlate with high values of serum propr...

    Authors: AnneMarie Gagnon, Moeber Mahzari, Heather A Lochnan and Alexander Sorisky
    Citation: Thyroid Research 2014 7:4
  7. Thyroid metastases account for approximately 1.4-3% of all malignancies of the thyroid gland. Thyroid metastases are most common in: clarocellular carcinoma of the kidney, lung cancer, breast cancer, malignant...

    Authors: Monika Koziołek, Anna Sieradzka, Lilianna Osowicz-Korolonek, Ewa Wentland-Kotwicka, Katarzyna Karpińska-Kaczmarczyk and Anhelli Syrenicz
    Citation: Thyroid Research 2014 7:1
  8. Studies based on laboratory data about thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference interval (RI) show conflicting results regarding the importance of using specific values by age group...

    Authors: Rosita Fontes, Claudia Regina Coeli, Fernanda Aguiar and Mario Vaisman
    Citation: Thyroid Research 2013 6:13
  9. Serum concentration of soluble interleukin-2 receptor (sIL-2R) has been established as a reliable marker of T-lymphocyte activation. However, there have been no reports describing the relationship between seru...

    Authors: Kae Hamamoto, Masaaki Inaba, Shinsuke Yamada, Maki Yoda, Koichiro Yoda, Hitoshi Goto, Masafumi Kurajoh and Hidenori Koyama
    Citation: Thyroid Research 2013 6:12
  10. Thyrotoxicosis is a cause of secondary osteoporosis. High concentrations of triiodotironine (T3) in Graves’ disease stimulate bone turnover, but it is unclear if euthyroidism will always normalize bone metabol...

    Authors: Monica A Ercolano, Monica L Drnovsek, Maria C Silva Croome, Monica Moos, Ana M Fuentes, Fanny Viale, Ulla Feldt-Rasmussen and Alicia T Gauna
    Citation: Thyroid Research 2013 6:11
  11. Fenton reaction (Fe2++H2O2→Fe3++OH+OH) is of special significance in the thyroid gland, as both its substrates, i.e. H2O2 and Fe2+, are required for thyroid hormone synthesis. Also iodine, an essential element ...

    Authors: Magdalena Milczarek, Jan Stępniak, Andrzej Lewiński and Małgorzata Karbownik-Lewińska
    Citation: Thyroid Research 2013 6:10
  12. In order to assess safety of radioactive iodine administration in the treatment of thyrotoxicosis, we measured concentrations of matrix metalloproteinase-2 (MMP-2), its main inhibitor – TIMP-2 (tissue inhibito...

    Authors: Andrzej Lewinski, Anna Brona, Krzysztof C Lewandowski, Diana Jedrzejuk, Anna Bohdanowicz-Pawlak, Elżbieta Skowronska-Jozwiak, Małgorzata Bienkiewicz and Andrzej Milewicz
    Citation: Thyroid Research 2013 6:9
  13. Associations between breast cancer and thyroid disorders are reported in numerous studies. Relationships between thyroperoxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb) and breast cancer have been ...

    Authors: Paweł Szychta, Wojciech Szychta, Adam Gesing, Andrzej Lewiński and Małgorzata Karbownik-Lewińska
    Citation: Thyroid Research 2013 6:8
  14. Hyperfunctioning nodules of the thyroid are thought to only rarely harbor thyroid cancer, and thus are infrequently biopsied. Here, we present the case of a patient with a hyperfunctioning thyroid nodule harbo...

    Authors: Sasan Mirfakhraee, Dana Mathews, Lan Peng, Stacey Woodruff and Jeffrey M Zigman
    Citation: Thyroid Research 2013 6:7
  15. The standard management in patients with thyroid nodules is to assess the risk of malignancy, based on cytological examination. On the other hand, there are thyroid patterns of ultrasound (US) image, associate...

    Authors: Zbigniew Adamczewski and Andrzej Lewiński
    Citation: Thyroid Research 2013 6:6
  16. Authors: Jacek Sygut, Aldona Kowalska, Janusz Słuszniak, Jacek Heciak, Janusz Kopczyński, Dominik Sygut, Kornelia Niemyska and Stanisław Góźdź
    Citation: Thyroid Research 2013 6(Suppl 2):A59

    This article is part of a Supplement: Volume 6 Supplement 2

  17. Authors: Magdalena Rudzińska, Damian Gaweł, Anna Stachurska, Hanna Domek, Jolanta Czerwińska, Mirosław Kiedrowski, Tomasz Stępień, Dariusz Lange and Barbara Czarnocka
    Citation: Thyroid Research 2013 6(Suppl 2):A51

    This article is part of a Supplement: Volume 6 Supplement 2

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