Volume 4 Supplement 1

New aspects of thyroid hormone synthesis and action


Edited by Heike Biebermann

  1. Research

    Cathepsin B trafficking in thyroid carcinoma cells

    The cysteine peptidase cathepsin B is important in thyroid physiology by being involved in prohormone processing initiated in the follicle lumen and completed in endo-lysosomal compartments. However, cathepsin...

    Sofia Tedelind, Silvia Jordans, Henrike Resemann, Galia Blum, Matthew Bogyo, Dagmar Führer and Klaudia Brix

    Thyroid Research 2011 4(Suppl 1):S2

    Published on: 3 August 2011

  2. Research

    Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

    The monocarboxylate transporter 8 (MCT8) is a member of the major facilitator superfamily (MFS) and transports specificly iodothyronines. MCT8 mutations are the underlying cause of a syndrome of severe X-linke...

    Gunnar Kleinau, Ulrich Schweizer, Anita Kinne, Josef Köhrle, Annette Grüters, Heiko Krude and Heike Biebermann

    Thyroid Research 2011 4(Suppl 1):S4

    Published on: 3 August 2011

  3. Review

    Transcriptional regulation by nonclassical action of thyroid hormone

    Thyroid hormone (TH) is essential for normal development, growth and metabolism. Its effects were thought to be principally mediated through triiodothyronine (T3), acting as a ligand for the nuclear TH recepto...

    Lars C Moeller and Martina Broecker-Preuss

    Thyroid Research 2011 4(Suppl 1):S6

    Published on: 3 August 2011

  4. Review

    Primary and secondary thyroid hormone transporters

    Thyroid hormones (TH) are essential for the development of the human brain, growth and cellular metabolism. Investigation of TH transporters became one of the emerging fields in thyroid research after the disc...

    Anita Kinne, Ralf Schülein and Gerd Krause

    Thyroid Research 2011 4(Suppl 1):S7

    Published on: 3 August 2011

  5. Research

    Molecular description of non-autoimmune hyperthyroidism at a neonate caused by a new thyrotropin receptor germline mutation

    Constitutively activating germline mutations in the thyrotropin receptor (TSHR) gene result in non-autoimmune hyperthyroidism and can be transmitted as a dominant trait or occur sporadically. These mutations a...

    Heike Biebermann, Franziska Winkler, Daniela Handke, Annette Grüters, Heiko Krude and Gunnar Kleinau

    Thyroid Research 2011 4(Suppl 1):S8

    Published on: 3 August 2011