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  1. Several meta-analyses have been performed comparing the use of a variety of ultrasonic devices in thyroidectomy to conventional procedures. These studies have shown the superiority of ultrasonic devices for mo...

    Authors: Hang Cheng, Ireena Soleas, Nicole C. Ferko, Jeffrey W. Clymer and Joseph F. Amaral
    Citation: Thyroid Research 2015 8:15
  2. Medullary thyroid cancer (MTC) is a C-cell neoplasm. Surgery remains its main treatment. Promising therapies based on tyrosine kinase inhibitors demand careful patient selection. We previously observed that tw...

    Authors: Thierry Ragot, Claire Provost, Aurélie Prignon, Régis Cohen, Michel Lepoivre and Sylvie Lausson
    Citation: Thyroid Research 2015 8:13
  3. Thyroperoxidase (TPO) is a membrane-bound protein essential for the production of thyroid hormones; because of this, TPO expression may be impaired in selected thyroid diseases. The goal of this study is to an...

    Authors: Yurena Caballero, Eudaldo M. López-Tomassetti, Julián Favre, José R. Santana, Juan J. Cabrera and Juan R. Hernández
    Citation: Thyroid Research 2015 8:12
  4. Circulating thyrotropin receptor messenger ribonucleic acid (TSHR mRNA) assay has been validated in the follow-up of differentiated thyroid carcinoma (DTC) because of its high sensitivity during thyroid hormon...

    Authors: Surasawadee Ausavarat, Jiraporn Sriprapaporn, Busara Satayaban, Wanna Thongnoppakhun, Aunchalee Laipiriyakun, Boontham Amornkitticharoen, Rujaporn Chanachai and Chaveevan Pattanachak
    Citation: Thyroid Research 2015 8:11
  5. The ratio of serum free triiodothyronine (FT3) to free thyroxine (FT4) has been shown to be constant in healthy adults. However, this ratio has been found to be decreased in athyreotic adult patients on levoth...

    Authors: Yuji Oto, Koji Muroya, Junko Hanakawa, Yumi Asakura and Masanori Adachi
    Citation: Thyroid Research 2015 8:10
  6. Stroke is the fifth leading cause of death and the primary cause of long-term adult disability in the United States. Increasing evidence suggests that low T3 levels immediately following acute ischemic stroke ...

    Authors: Lena M. O’Keefe, Sarah E. Conway, Alexandra Czap, Carl D. Malchoff, Sharon Benashski, Gilbert Fortunato, Ilene Staff and Louise D. McCullough
    Citation: Thyroid Research 2015 8:9
  7. Treatment of differentiated thyroid carcinoma (DTC) includes suppression of TSH with levothyroxine therapy, which may negatively influence bone mineral density (BMD), but the effects are controversial. We aime...

    Authors: Thaís Gomes de Melo, Lígia Vera Montalli da Assumpção, Allan de Oliveira Santos and Denise Engelbrecht Zantut-Wittmann
    Citation: Thyroid Research 2015 8:7
  8. The heart is a major target organ for thyroid hormone action. Severe overt hypothyroidism can result in diastolic hypertension, lowered cardiac output, impaired left ventricular contractility and diastolic rel...

    Authors: Apostolos Chatzitomaris, Michael Scheeler, Michael Gotzmann, Roland Köditz, Janice Schildroth, Kathy Miriam Knyhala, Volkmar Nicolas, Christoph Heyer, Andreas Mügge, Harald H. Klein and Johannes W. Dietrich
    Citation: Thyroid Research 2015 8:6
  9. Rare diseases are usually defined as entities affecting less than 1 person per 2,000. About 7,000 different rare entities are distinguished and, among them, rare diseases of the thyroid gland. Although not fre...

    Authors: Katarzyna Lacka and Adam Maciejewski
    Citation: Thyroid Research 2015 8:5
  10. Patients with metastases to the thyroid from renal cell carcinoma (RCC) that need surgical management are not many and unfamiliar to clinicians and thyroid endocrinologists. Therefore, little information is av...

    Authors: Kaoru Kobayashi, Mitsuyoshi Hirokawa, Tomonori Yabuta, Mitsuhiro Fukushima, Hiroo Masuoka, Takuya Higashiyama, Minoru Kihara, Yasuhiro Ito, Akihiro Miya, Nobuyuki Amino and Akira Miyauchi
    Citation: Thyroid Research 2015 8:4
  11. The thyroid undergoes a variety of physiological changes during pregnancy. The relatively low iodine levels seen in pregnancy have been implicated in thyroid growth during this time. Management of thyroid canc...

    Authors: Manish M George, Jay Goswamy and Susannah E Penney
    Citation: Thyroid Research 2015 8:3
  12. Most of our knowledge on the mechanisms of thyroid hormone (TH) dependent brain development is based on clinical observations and animal studies of maternal/fetal hypothyroidism. THs play an essential role in ...

    Authors: R G Ahmed
    Citation: Thyroid Research 2015 8:2
  13. In normal conditions FSHR are expressed in granulosa cells of the ovary and Sertoli cells of the testis. They can be expressed also in gonadal tumours. However, recently the expression of FSHR was found in tum...

    Authors: Marek Pawlikowski, Julita Fuss-Chmielewska, Maria Jaranowska, Hanna Pisarek, Robert Kubiak and Katarzyna Winczyk
    Citation: Thyroid Research 2015 8:1
  14. Loss of bone mineral density due to osteoporosis is the main cause of fragility fractures and leads to dropped quality of life and increased mortality. Disturbance of balance between bone formation and bone re...

    Authors: Dominika Tuchendler and Marek Bolanowski
    Citation: Thyroid Research 2014 7:12
  15. The cyclooxygenases are a group of enzymes catalyzing the formation of prostaglandins from arachidonic acid. Cyclooxygenase-1 (COX-1) is a constitutive form, thought to be a “housekeeping gene”, with constant ...

    Authors: Kinga Krawczyk-Rusiecka, Katarzyna Wojciechowska-Durczynska, Anna Cyniak-Magierska, Arkadiusz Zygmunt and Andrzej Lewinski
    Citation: Thyroid Research 2014 7:10
  16. The cell-mediated immune process by CD4+ and CD8+ lymphocyte subsets of T-cells has a major role in the pathogenesis of Hashimoto’s thyroiditis (HT). However, the exact mechanisms of initiation and progression...

    Authors: Teslime Ayaz, Serap Baydur Sahin, Osman Zikrullah Sahin, Medine Cumhur Cure, Fatih Sumer and Kadir Ilkkilic
    Citation: Thyroid Research 2014 7:11
  17. The pre-surgical selection of thyroid nodules with indeterminate cytology (Thy 3 according to British Thyroid Association) after fine-needle aspiration biopsy (FNAB) is currently required in order to reduce un...

    Authors: Massimo Giusti, Claudia Campomenosi, Stefano Gay, Barbara Massa, Enzo Silvestri, Eleonora Monti and Giovanni Turtulici
    Citation: Thyroid Research 2014 7:9
  18. Preoperative diagnostic investigations of nodular goiter are based on two main examinations: ultrasonography of the thyroid gland and ultrasound-guided fine-needle aspiration biopsy. So far, FNAB has been the ...

    Authors: Anhelli Syrenicz, Monika Koziołek, Andrzej Ciechanowicz, Anna Sieradzka, Agnieszka Bińczak-Kuleta and Miłosz Parczewski
    Citation: Thyroid Research 2014 7:6
  19. Whereas oxidative reactions occur in all tissues and organs, the thyroid constitutes such an organ, in which oxidative processes are indispensable for physiological functions. In turn, numerous metabolic react...

    Authors: Agnieszka Kokoszko-Bilska, Jan Stepniak, Andrzej Lewinski and Malgorzata Karbownik-Lewinska
    Citation: Thyroid Research 2014 7:5

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