Articles

Treatment related morbidity in differentiated thyroid cancer–a survey of clinicians

Differentiated thyroid cancer (DTC) has excellent long term survival in most patients. Long-term treatment related morbidity is therefore important, but may not be well characterised. The aim of this study was...

Authors: Ovie Edafe, Jonathan Wadsley, Barney J Harrison and Sabapathy P Balasubramanian

Thyroid disease in insulin-treated patients with type 2 diabetes: a retrospective study

Diabetes mellitus and thyroid diseases frequently coexist. In order to evaluate how thyroid disorders interfere with glycemic control, we analysed insulin-treated type 2 diabetes patients with thyroid disease.

Authors: Valerie Witting, Dominik Bergis, Dilek Sadet and Klaus Badenhoop

From the diagnostic investigations of goiter to the diagnosis of lung cancer – case study

Thyroid metastases account for approximately 1.4-3% of all malignancies of the thyroid gland. Thyroid metastases are most common in: clarocellular carcinoma of the kidney, lung cancer, breast cancer, malignant...

Authors: Monika Koziołek, Anna Sieradzka, Lilianna Osowicz-Korolonek, Ewa Wentland-Kotwicka, Katarzyna Karpińska-Kaczmarczyk and Anhelli Syrenicz

Reference interval of thyroid stimulating hormone and free thyroxine in a reference population over 60 years old and in very old subjects (over 80 years): comparison to young subjects

Studies based on laboratory data about thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference interval (RI) show conflicting results regarding the importance of using specific values by age group...

Authors: Rosita Fontes, Claudia Regina Coeli, Fernanda Aguiar and Mario Vaisman

Increased soluble IL-2 receptor levels in serum from a patient with painless thyroiditis

Serum concentration of soluble interleukin-2 receptor (sIL-2R) has been established as a reliable marker of T-lymphocyte activation. However, there have been no reports describing the relationship between seru...

Authors: Kae Hamamoto, Masaaki Inaba, Shinsuke Yamada, Maki Yoda, Koichiro Yoda, Hitoshi Goto, Masafumi Kurajoh and Hidenori Koyama

Negative correlation between bone mineral density and TSH receptor antibodies in long-term euthyroid postmenopausal women with treated Graves’ disease

Thyrotoxicosis is a cause of secondary osteoporosis. High concentrations of triiodotironine (T3) in Graves’ disease stimulate bone turnover, but it is unclear if euthyroidism will always normalize bone metabol...

Authors: Monica A Ercolano, Monica L Drnovsek, Maria C Silva Croome, Monica Moos, Ana M Fuentes, Fanny Viale, Ulla Feldt-Rasmussen and Alicia T Gauna

Potassium iodide, but not potassium iodate, as a potential protective agent against oxidative damage to membrane lipids in porcine thyroid

Fenton reaction (Fe²⁺+H₂O₂→Fe³⁺+^•OH+OH⁻) is of special significance in the thyroid gland, as both its substrates, i.e. H₂O₂ and Fe²⁺, are required for thyroid hormone synthesis. Also iodine, an essential element ...

Authors: Magdalena Milczarek, Jan Stępniak, Andrzej Lewiński and Małgorzata Karbownik-Lewińska

Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1

In order to assess safety of radioactive iodine administration in the treatment of thyrotoxicosis, we measured concentrations of matrix metalloproteinase-2 (MMP-2), its main inhibitor – TIMP-2 (tissue inhibito...

Authors: Andrzej Lewinski, Anna Brona, Krzysztof C Lewandowski, Diana Jedrzejuk, Anna Bohdanowicz-Pawlak, Elżbieta Skowronska-Jozwiak, Małgorzata Bienkiewicz and Andrzej Milewicz

TSH receptor antibodies have predictive value for breast cancer – retrospective analysis

Associations between breast cancer and thyroid disorders are reported in numerous studies. Relationships between thyroperoxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb) and breast cancer have been ...

Authors: Paweł Szychta, Wojciech Szychta, Adam Gesing, Andrzej Lewiński and Małgorzata Karbownik-Lewińska

A solitary hyperfunctioning thyroid nodule harboring thyroid carcinoma: review of the literature

Hyperfunctioning nodules of the thyroid are thought to only rarely harbor thyroid cancer, and thus are infrequently biopsied. Here, we present the case of a patient with a hyperfunctioning thyroid nodule harbo...

Authors: Sasan Mirfakhraee, Dana Mathews, Lan Peng, Stacey Woodruff and Jeffrey M Zigman

Proposed algorithm for management of patients with thyroid nodules/focal lesions, based on ultrasound (US) and fine-needle aspiration biopsy (FNAB); our own experience

The standard management in patients with thyroid nodules is to assess the risk of malignancy, based on cytological examination. On the other hand, there are thyroid patterns of ultrasound (US) image, associate...

Authors: Zbigniew Adamczewski and Andrzej Lewiński

Obliteration of thyroid arteries as a new method of treatment of thyroid diseases

Authors: Grzegorz Kamiński and Andrzej Jaroszuk

Evaluation of the effectiveness of iodine prophylaxis in Poland based on the examination of school-age children in Opoczno

Authors: Arkadiusz Zygmunt

Feasibility and efficacy of neck dissections in patients with thyroid cancer

Authors: Małgorzata Wierzbicka, Edyta Gurgul, Elżbieta Waśniewska-Okupniak, Maria Gryczyńska, Tomasz Piorunek and Marek Ruchała

The risk of iodine deficiency in the current model of iodine prophylaxis in Poland

Authors: Zbigniew Szybiński

Effectiveness analysis of papillary thyroid carcinoma (PTC) diagnostics in Holycross Cancer Centre (HCC) in Kielce according to fine needle aspiration biopsy quality assurance program in pathology department between years 2001 and 2012

Authors: Jacek Sygut, Aldona Kowalska, Janusz Słuszniak, Jacek Heciak, Janusz Kopczyński, Dominik Sygut, Kornelia Niemyska and Stanisław Góźdź

Local renin-angiotensin system in the thyroid – myth or fact?

Authors: Mariusz Stasiołek

Various types of autoimmunological diseases of thyroid gland

Authors: Stanisław Sporny

Long-term thyroid hormone replacement therapy

Authors: Jerzy Sowiński

The role of the transcription factor - Prospero homeobox 1 (Prox1) in the biology of differentiated thyroid cancer - the effect of the expression of Prox1 on migration and invasiveness of thyroid cancer cells

Authors: Magdalena Rudzińska, Damian Gaweł, Anna Stachurska, Hanna Domek, Jolanta Czerwińska, Mirosław Kiedrowski, Tomasz Stępień, Dariusz Lange and Barbara Czarnocka

Changes of the hypothalamic-pituitary-thyroid axis in aging

Authors: Monika Puzianowska-Kuźnicka

Permanent and transient congenital hypothyroidism in full-term and preterm born infants

Authors: Elżbieta Petriczko and Mieczysław Walczak

Non-autoimmune hyperthyroidism caused by thyroid-stimulating hormone receptor germline mutations - 2012 European Thyroid Association Guidelines

Authors: R Paschke, M Niedziela, B Vaidya, L Persani, B Rapoport and J Leclere

Etiopathogenesis of Graves-Basedow disease; where we are and where we are going

Authors: Janusz Nauman

The flow of genetic information – the role of thyroid hormones in the regulation of gene expression

Authors: Alicja Nauman

Natural history of subclinical hypothyroidism in children and adolescents

Authors: Ewa Małecka-Tendera

Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin

Authors: Andrzej Lewiński, Anna Brona, Diana Jędrzejuk, Anna Bohdanowicz-Pawlak, Krzysztof C Lewandowski, Małgorzata Bieńkiewicz and Andrzej Milewicz

Ability of proper application of ultrasound (US) and a fine needle aspiration biopsy (FNAB) in the management of thyroid nodules/focal lesions in patients with coexisting additional worrying clinical signs and symptoms

Authors: Andrzej Lewiński and Zbigniew Adamczewski

Odd thyroid function tests results: interference versus non-compliance

Authors: Krzysztof C Lewandowski

Rare thyroid diseases

Authors: Katarzyna Łącka

Thyroid hormones and male reproductive system

Authors: Krzysztof Kula

Comparison of clinical examination with orbital MRI evaluation in patients with thyroid orbitopathy - do we need imaging and when?

Authors: Aleksandra Król, Jolanta Krajewska, Barbara Michalik, Ewa Paliczka-Cieślik, Michał Kalemba, Beata Jurecka-Lubieniecka, Kornelia Hasse-Lazar, Sylwia Szpak-Ulczok, Łukasz Zarudzki and Barbara Jarząb

Diagnosis of follicular thyroid cancer based on the presence of a metastasis in the vertebral column – case report

Authors: Monika Koziołek, M Wolska, A Sieradzka, M Jakuszewski, K Karpińska-Kaczmarczyk, M Bilski and Anhelli Syrenicz

Variation of the epidemiological structure of thyroid cancer between year 2000 and 2012

Authors: Aldona Kowalska, Jacek Sygut, Janusz Słuszniak, A Walczyk, Iwona Pałyga, Danuta Gąsior-Perczak, K Gadawska-Juszczyk, D Szyska-Skrobot, T Trybek, S Hurej, Ryszard Mężyk and Stanisław Góźdź

Vitamin D and thyroid cancer

Authors: Jan Komorowski, Roman Krupiński, Jan Sopiński, Krzysztof Kuzdak, Henryk Stępień, Hanna Ławnicka and Tomasz Stępień

Thyroid disorders and pregnancy

Authors: Małgorzata Karbownik-Lewińska

What is the best therapeutic approach if the initial glucocorticoids therapy of active Graves’ orbitopathy fails?

Authors: Helena Jastrzębska

Treatment of advanced thyroid cancer refractory to therapy

Authors: Barbara Jarząb

Endocrine Disrupting Compounds – do we need to consider thyroid hormones? Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Authors: Arno C Gutleb

Thyrotoxicosis and pregnancy

Authors: Małgorzata Gietka-Czernel

The role of 18F-FDG PET/CT testing in the management of a papillary thyroid carcinoma

Authors: Agnieszka Florczak and Andrea d'Amico

Perspectives in the management of thyroid orbitopathy

Authors: Jacek Daroszewski

Thyroid surgery – intraoperative localization and protection of important structures of the neck

Authors: Jan Brzeziński

Do thyroid peroxidase antibodies influence risk of cardiovascular diseases before and after treatment of hyperthyroidism?

Authors: Anna Brona, Anna Bohdanowicz-Pawlak, J Jakubowska, Diana Jędrzejuk and Andrzej Milewicz

Interactions of metabolic syndrome and thyroid hormones

Authors: Georg Brabant

Role of Th17 cells and IL-17, IL-23 cytokines in pathogenesis of autoimmune thyroid disease in children

Authors: Artur Bossowski, M Moniuszko, M Dabrowska, M Rusak, M Jeznach, A Bodzenta-Łukaszyk and A Bossowska

MicroRNAs in thyroid function and pathology

Authors: Joanna Bogusławska

Is the treatment with pulses of methylprednisolone safe?

Authors: Tomasz Bednarczuk and Piotr Miśkiewicz

Combined glucocorticoid and orbital radiation therapy – literature review and clinical experience

Authors: Agata Bałdys-Waligórska

Medullary carcinoma of the thyroid: an update

Authors: Maria Alevizaki