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  1. Thyrotoxicosis is common disorder among endocrine dysfunctions. It is not rare that the free thyroid hormone level exceeds the measurement range of immunoassay. Such extreme high concentration of free thyroid ...

    Authors: Yuko Ito, Satoru Suzuki, Yoshiko Matsumoto, Chiyo Ohkouchi, Satoshi Suzuki, Manabu Iwadate, Sanae Midorikawa, Susumu Yokoya, Shinichi Suzuki and Hiroki Shimura
    Citation: Thyroid Research 2020 13:4
    Content type: Case report Published on:

  4. Anti-Müllerian hormone (AMH) decreases acutely after post-surgical radioactive iodine (RAI) ablation in females with differentiated thyroid cancer (DTC).

    Authors: Miranda Mittica, Andrea Dotto, Martina Comina, Marsida Teliti, Eleonora Monti and Massimo Giusti
    Citation: Thyroid Research 2020 13:1
    Content type: Research Published on:

  5. Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be ...

    Authors: Dorota Walasik-Szemplińska, Grzegorz Kamiński and Iwona Sudoł-Szopińska
    Citation: Thyroid Research 2019 12:13
    Content type: Review Published on:

  6. Thyroid swellings enlarge caudally into the mediastinum behind the sternum. Pre-sternal swelling of thyroid origin is very rare. We present our case of pre-sternal thyroid swelling which was albeit a surprisin...

    Authors: Lovenish Bains, Sushant Bhatia, Rohit Kaushik, Sudhir Kumar Jain, Chandra Bhushan Singh, Shramana Mandal and Daljit Kaur
    Citation: Thyroid Research 2019 12:12
    Content type: Case report Published on:

  8. Well-differentiated thyroid carcinoma is defined as locally advanced in the presence of an extra thyroid extension, e.g., when the surrounding structures such as the trachea, larynx, esophagus and main blood v...

    Authors: Alessio Metere, Valerio Aceti and Laura Giacomelli
    Citation: Thyroid Research 2019 12:10
    Content type: Review Published on:

  9. A high body fat percentage has a specific effect on activation of the hypothalamic-pituitary-thyroid axis. On the other hand, a slight change in thyroid hormones can affect metabolism and body composition as w...

    Authors: Maryam Karkhaneh, Mostafa Qorbani, Asal Ataie-Jafari, Mohamad Reza Mohajeri-Tehrani, Hamid Asayesh and Saeed Hosseini
    Citation: Thyroid Research 2019 12:9
    Content type: Research Published on:

  10. Resistance to thyroid hormone (RTH) usually features a syndrome of inappropriate secretion of thyroid-stimulating hormone (SITSH) without suppression of the typical high thyroid hormone levels. However, some p...

    Authors: Tomoko Nagamine, Jaeduk Yoshimura Noh, Naoya Emoto, Takahito Kogai, Akira Hishinuma, Fumitaka Okajima and Hitoshi Sugihara
    Citation: Thyroid Research 2019 12:8
    Content type: Case report Published on:

  11. Resistance to thyroid hormones is a very rare condition, which is often misdiagnosed and mistreated. The cases where there is a concomitant autoimmune thyroid disorder are ultra-rare and particularly challengi...

    Authors: Todor Arsov, Chengmei Xie, Nan Shen, Dan Andrews, Carola G. Vinuesa and Olivija Vaskova
    Citation: Thyroid Research 2019 12:7
    Content type: Case report Published on:

  12. Aberrant iodine intake and thyroid autoimmunity affect thyroid function. Deficiencies of iodine including thyroid disorders have serious impact on child physical and mental development. This study was conducte...

    Authors: Binaya Tamang, Saroj Khatiwada, Basanta Gelal, Shrijana Shrestha, Kishun Deo Mehta, Nirmal Baral, Gauri Shankar Shah and Madhab Lamsal
    Citation: Thyroid Research 2019 12:6
    Content type: Research Published on:

  14. To semi-quantitatively analyze liver uptake of I-131 in diagnostic and post-therapy scans by calculating hepatic to thigh ratios (HTR) and evaluate its clinical significance in management of differentiated thy...

    Authors: Prasanta K. Pradhan, Suruchi Jain, Madhusudhanan Ponnuswamy, Amitabh Arya and Manish Ora
    Citation: Thyroid Research 2019 12:4
    Content type: Research Published on:

  15. Thyrotoxicosis is a clinical state that results from inappropriately high thyroid hormone action in tissues. Although it is one of the common endocrine disorders, there is scarcity of data on the management of...

    Authors: Eyob Alemayehu Gebreyohannes, Emneteab Mesfin Ayele, Soliana Alemayehu Tesfaye and Mohammed Assen Seid
    Citation: Thyroid Research 2019 12:3
    Content type: Research Published on:

  16. Both overt hypothyroidism as well as minor elevations of serum thyrotropin (TSH) levels associated with thyroid hormones within their respective reference ranges (termed subclinical hypothyroidism) are relativ...

    Authors: Owain Leng and Salman Razvi
    Citation: Thyroid Research 2019 12:2
    Content type: Review Published on:

  18. Thyroid malignancy constitutes the sixth common cancer type in the United Arab Emirates (UAE). There are no epidemiological data outlining the prevalence of cancer in thyroid nodules, nor previous analysis of ...

    Authors: Eiman Alseddeeqi, Raqwana Baharoon, Rawia Mohamed, Jenan Ghaith, Abeer Al-Helali and Luai A. Ahmed
    Citation: Thyroid Research 2018 11:17
    Content type: Research Published on:

  19. Nodular lesions of the thyroid gland, including papillary thyroid carcinoma (PTC), may be difficult to diagnose by imaging, such as in ultrasonic echo testing, or by needle biopsy. Definitive diagnosis is made...

    Authors: Rumi Hino, Naoko Inoshita, Toyoki Yoshimoto, Makiko Ogawa, Daishu Miura, Ryoko Watanabe, Kenta Watanabe, Mako Kamiya and Yasteru Urano
    Citation: Thyroid Research 2018 11:16
    Content type: Research Published on:

  20. For the differential diagnosis of medullary thyroid carcinoma (MTC) on thyroid nodules, ultrasound-guided fine-needle aspiration cytology is a useful and safe procedure, but its diagnostic accuracy is not high...

    Authors: Minoru Kihara, Mitsuyoshi Hirokawa, Takumi Kudo, Toshitetsu Hayashi, Masatoshi Yamamoto, Hiroo Masuoka, Takuya Higashiyama, Mitsuhiro Fukushima, Yasuhiro Ito, Akihiro Miya and Akira Miyauchi
    Citation: Thyroid Research 2018 11:15
    Content type: Research Published on:

  21. On 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET), diffuse uptake in the thyroid gland is often observed in patients with Hashimoto’s thyroiditis. In this study, we evaluated the factors associat...

    Authors: Naoki Edo, Koji Morita, Miki Sakamoto, Tatsuro Kaminaga, Hiromi Edo, Erina Okamura, Masumi Ogawa, Kazuhisa Tsukamoto, Hiroko Okinaga and Toshio Ishikawa
    Citation: Thyroid Research 2018 11:14
    Content type: Research Published on:

  22. The activating mutation BRAFV600E is a frequent genetic event in papillary thyroid carcinomas (PTC). Mutation BRAFV600E is associated with the loss of a sodium/iodine symporter (NIS), and subsequent radioiodide-r...

    Authors: Honglai Zhang and Dong Chen
    Citation: Thyroid Research 2018 11:13
    Content type: Research Published on:

  24. Malignant biphasic tumor also known as carcinosarcoma is an uncommon neoplasm that is composed of both malignant epithelial and mesenchymal components. Most reported cases of carcinosarcoma affect the female g...

    Authors: Jing Yang, Carmen Sarita-Reyes, David Kindelberger and Qing Zhao
    Citation: Thyroid Research 2018 11:11
    Content type: Case report Published on:

  25. Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary, histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to diagnose on clinical basis or imaging ...

    Authors: Mohamed S. Al Hassan, Tamer Saafan, Walid El Ansari, Afaf A. Al Ansari, Mahmoud A. Zirie, Hanan Farghaly and Abdelrahman Abdelaal
    Citation: Thyroid Research 2018 11:10
    Content type: Case report Published on:

  26. Iodine is important for thyroid hormone synthesis, and iodine deficiency in pregnancy may impair fetal neurological development. As perchlorate and thiocyanate inhibit sodium-iodide symporter reducing the tran...

    Authors: Bridget A. Knight, Beverley M. Shields, Xuemei He, Elizabeth N. Pearce, Lewis E. Braverman, Rachel Sturley and Bijay Vaidya
    Citation: Thyroid Research 2018 11:9
    Content type: Research Published on:

  27. There is little information regarding the natural course of hypoechoic thyroid lesions that are probable or possible thyroid lymphoma based on fine needle aspiration cytology (FNAC) results.

    Authors: Tomoe Nakao, Mitsushige Nishikawa, Mako Hisakado, Toshihiko Kasahara, Takumi Kudo, Eijun Nishihara, Mitsuru Ito, Shuji Fukata, Hirotoshi Nakamura, Mitsuyoshi Hirokawa and Akira Miyauchi
    Citation: Thyroid Research 2018 11:8
    Content type: Research Published on:

  28. Evidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results,...

    Authors: Kris Poppe, Flora Veltri and Candice Autin
    Citation: Thyroid Research 2018 11:7
    Content type: Commentary Published on:

  29. Gastric ulcers are mucosal discontinuities that may extend into the mucosa, submucosa or even deeper. They result from an imbalance between mucosal aggressors and protective mechanisms that include the mucus b...

    Authors: Jackline Namulema, Miriam Nansunga, Charles Drago Kato, Muhammudu Kalange and Samuel Babafemi Olaleye
    Citation: Thyroid Research 2018 11:6
    Content type: Research Published on:

  31. The thyroid gland is resistant to microbial infection, because of its organ characteristics such as encapsulation, iodine content, and rich blood supply. Therefore, acute suppurative thyroiditis (AST), as a ba...

    Authors: Hazuki Otani, Masakazu Notsu, Sayo Koike, Miwa Morita, Masahiro Yamamoto, Mika Yamauchi, Takahumi Fuchiwaki, Ichiro Morikura, Noriaki Aoi, Hideyuki Kawauchi, Teruaki Iwabashi, Asuka Araki, Noriyoshi Ishikawa, Riruke Maruyama and Toshitsugu Sugimoto
    Citation: Thyroid Research 2018 11:4
    Content type: Case report Published on:

  32. We aimed to study the validity of six published ultrasound criteria for risk stratification of thyroid nodules in the former severely iodine deficient population of Austria.

    Authors: Christina Tugendsam, Veronika Petz, Wolfgang Buchinger, Brigitta Schmoll-Hauer, Iris Pia Schenk, Karin Rudolph, Michael Krebs and Georg Zettinig
    Citation: Thyroid Research 2018 11:3
    Content type: Research Published on:

  33. Autoimmune thyroid disorders (AITD) broadly include Graves’ disease and Hashimoto’s thyroiditis which are the most common causes of thyroid gland dysfunctions. These disorders develop due to complex interactio...

    Authors: Marta Rydzewska, Michał Jaromin, Izabela Elżbieta Pasierowska, Karlina Stożek and Artur Bossowski
    Citation: Thyroid Research 2018 11:2
    Content type: Short report Published on:

  34. Whilst trials of combination levothyroxine/liothyronine therapy versus levothyroxine monotherapy for thyroid hormone replacement have not shown any superiority, there remains a small subset of patients who do ...

    Authors: Colin Dayan and Vijay Panicker
    Citation: Thyroid Research 2018 11:1
    Content type: Review Published on:

  35. Recurrent papillary thyroid carcinoma (PTC) beyond the first two decades of definitive treatment (i.e. total thyroidectomy and radioactive iodine ablation) is a rare occurrence.

    Authors: Yaw Amoako-Tuffour, M. Elise Graham, Martin Bullock, Matthew H. Rigby, Jonathan Trites, S. Mark Taylor and Robert D. Hart
    Citation: Thyroid Research 2017 10:8
    Content type: Case report Published on:

  36. Hyalinizing trabecular tumors (HTT) are rare follicular cell-derived tumors of the thyroid gland that are infrequently reported in otolaryngology literature. We present here an interesting case of HTT which pr...

    Authors: Dustin J. Jones, Christopher R. Kieliszak, Sanjay S. Patel and Christopher R. Selinsky
    Citation: Thyroid Research 2017 10:7
    Content type: Case report Published on:

  37. Medullary thyroid carcinoma (MTC) accounts for 1-2% of all thyroid cancers. The clinical course of metastatic disease can be indolent. Our aim was to characterize the natural history of disease to evaluate the...

    Authors: Georgia Geller, Janessa Laskin, Winson Y. Cheung and Cheryl Ho
    Citation: Thyroid Research 2017 10:6
    Content type: Research Published on:

  39. Pregnancy and delivery markedly influence thyroid function. However, the comparative prevalence of gestational thyrotoxicosis (GT), new onset of Graves’ disease during pregnancy (GD during pregnancy), postpart...

    Authors: Akane Ide, Nobuyuki Amino, Takumi Kudo, Waka Yoshioka, Mako Hisakado, Eijun Nishihara, Mitsuru Ito, Shuji Fukata, Hirotoshi Nakamura and Akira Miyauchi
    Citation: Thyroid Research 2017 10:4
    Content type: Research Published on:

  40. Struma ovarii is a rare monodermal germ cell tumor where the ovary is comprised of at least half thyroid tissue. This phenomenon may indicate an embryological origin.

    Authors: J. Colin Boyd, Blair A. Williams, Matthew H. Rigby, Katharina Kieser, Saul Offman, Hemlata Shirsat, Jonathan R. B. Trites, S. Mark Taylor and Robert D. Hart
    Citation: Thyroid Research 2017 10:3
    Content type: Case report Published on:

  41. Authors: Luigi Bartalena, Eric Fliers, Nicola Hellen, Peter N. Taylor, Arron Lacey, Daniel Thayer, Mohd Draman Yusof, Arshiya Tabasum, Illaria Muller, Luke Marsh, Marian Ludgate, Alex Rees, Kristien Boelaert, Shiao Chan, Scott Nelson, Aled Rees…
    Citation: Thyroid Research 2017 10(Suppl 1):2
    Content type: Meeting abstracts Published on:

    This article is part of a Supplement: Volume 10 Supplement 1

  43. Authors: Leonard Wartofsky, Peter Smyth, Josef Köhrle, Ryszard Anielski, Marian Slowiaczek, Pawel Orlicki, Rafal Czepczynski, Jacek Daroszewski, Alicja Hubalewska-Dydejczyk, Aldona Kowalska, Maria Kurowska, Joanna Malicka, Anna Oszywa-Chabros, Agnieszka Zwolak, Jerzy S. Tarach, Krzysztof C. Lewandowski…
    Citation: Thyroid Research 2016 9(Suppl 1):6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  44. Hypothyroidism is a common condition, particularly in the older population. Thyroid hormone requirements change with age and serum TSH levels also alter, especially in older patients. However, in practice labo...

    Authors: Salman Razvi, Lorna Ingoe, Vicky Ryan, Simon H. S. Pearce and Scott Wilkes
    Citation: Thyroid Research 2016 9:5
    Content type: Research Published on:

  45. Although the majority of thyroid nodules are benign the process of excluding malignancy is challenging and sometimes involves unnecessary surgical procedures. We explored the development of a predictive model ...

    Authors: Justyna Witczak, Peter Taylor, Jason Chai, Bethan Amphlett, Jean-Marc Soukias, Gautam Das, Brian P. Tennant, John Geen and Onyebuchi E. Okosieme
    Citation: Thyroid Research 2016 9:4
    Content type: Research Published on:

  46. It is eight years since Thyroid Research was launched with an aim to enhance opportunities for scientists and clinicians, working in the rapidly advancing field of thyroidology, to publish their research (Thyroid...

    Authors: Bijay Vaidya and Andrzej Lewinski
    Citation: Thyroid Research 2016 9:3
    Content type: Editorial Published on:

  48. A change in a thyrometabolic state from severe hypothyroidism to thyrotoxicosis is very uncommon, but possible in some circumstances.

    Authors: Krzysztof Lewandowski, Katarzyna Dąbrowska, Jacek Makarewicz and Andrzej Lewiński
    Citation: Thyroid Research 2016 9:1
    Content type: Case report Published on:

  50. Though compliance (or adherence) problems, as well as inappropriate levothyroxine (L-T4) intake (e.g. with meal, other drugs or certain foods that can significantly affect absorption) are very common, the issue i...

    Authors: Krzysztof C. Lewandowski, Katarzyna Dąbrowska, Iwona Komorowska-Dudek and Andrzej Lewiński
    Citation: Thyroid Research 2015 8:16
    Content type: Case report Published on:
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