Articles

Endoscopic intranasal orbital decompression in the course of Graves’ orbitopathy

Authors: Antoni Krzeski and Mirosław J Szczepański

The role of somatostatin analogues in treatment of TSH secreting pituitary adenomas

Authors: Wojciech Zgliczyński, Piotr Zdunowski, Izabella Czajka-Oraniec, Wojciech Jeske and Grzegorz Zieliński

Recurrence of optic nerve neuropathy - a possible side effect of intravenous methylprednisolone pulses treatment

Authors: Katarzyna Trautsolt, Piotr Miśkiewicz, A Jabłońska, A Samsel, N Wołczańska, D Kęcik, Antoni Krzeski and Tomasz Bednarczuk

Hashimoto’s disease - from theory to practice

Authors: Anhelli Syrenicz

Evaluation of ultrasound-guided fine needle aspiration biopsy (USG-FNAB) of thyroid nodules: 12 years of accepted diagnostic algorithm in Holycross Cancer Centre (HCC) in Kielce

Authors: Jacek Sygut, Aldona Kowalska, Janusz Słuszniak, Jacek Heciak, Janusz Kopczyński, Dominik Sygut, Kornelia Niemyska and Stanisław Góźdź

Curiosa in fine needle aspiration biopsy of the thyroid gland

Authors: Stanisław Sporny

Clinical experience in the management of patients with Graves' orbitopathy treated according to the novel protocol of glucocorticoid therapy designed in the Department of Endocrinology, Metabolism and Internal Medicine of Poznan University of Medical Sciences

Authors: Jerzy Sowiński, Nadia Sawicka, Agnieszka Skiba and Marek Ruchała

Maintenance of iodine intake

Authors: Peter PA Smyth, Robert Burns, Michael Casey, Ru Jin Huang, Thorsten Hoffman, Colin O’Dowd, Harald Berresheim and Colm O’Herlihy

Imaging techniques in diagnostics, differentiation and monitoring of different types of thyroiditis

Authors: Marek Ruchała and Ewelina Szczepanek-Parulska

Molecular mechanism of thyroid hormone action in carcinogenesis

Authors: Agnieszka Piekiełko-Witkowska

Aberrant expression of follicle stimulating hormone receptors (FSHR) in thyroid neoplasia

Authors: Marek Pawlikowski, Hanna Pisarek, Robert Kubiak, Maria Jaranowska, Julita Fuss-Chmielewska and Katarzyna Winczyk

The correct interpretation of thyroid FNAB cytological result by the endocrinologist as a basis for further optimal diagnostics and treatment

Authors: Andrzej Lewiński

The assessment of side effects of tyrosine kinase inhibitors (TKI) applied in patients with advanced thyroid cancer (TC) - one centre experience

Authors: Jolanta Krajewska, Aleksandra Kukulska, Ewa Paliczka-Cieślik, Daria Handkiewicz-Junak, Tomasz Gawlik, Tomasz Olczyk, Aleksandra Kropińska, Aleksander Skoczylas, Barbara Michalik and Barbara Jarząb

Metastasis to the thyroid gland as the first clinical manifestation of lung cancer – case report

Authors: Monika Koziołek, A Sieradzka, E Wentland-Kotwicka, M Machaj, A Makszewska, A Dubińska-Walczak and Anhelli Syrenicz

Picture of thyroid cancer in 2012

Authors: Aldona Kowalska

Effect of triiodothyronine on hyperandrogenism in women

Authors: Gintautas Kazanavicius, I Purtokaite-Labutiniene, D Kozloviene, V Kruminis and E Kreivaitiene

The ATA guidelines of thyrotoxicosis

Authors: Roman Junik

Amiodarone and the thyroid dysfunction

Authors: Helena Jastrzębska

How far are we from understanding the genetic basis of Hashimoto’s thyroiditis?

Authors: Alicja Hubalewska-Dydejczyk

The propeptide of human thyroid peroxidase is not required for its cellular, enzymatic or immunological activity

Authors: Marlena Godlewska, M Góra, AM Buckle, BT Porebski, EH Kemp, W Krasuska, BJ Sutton, JP Banga and Barbara Czarnocka

Diagnostic performance evaluation of post-operative serum calcitonin (CT) levels as a factor for good prognosis in medullary thyroid carcinoma (MTC)

Authors: Danuta Gąsior-Perczak, Aldona Kowalska, Iwona Pałyga, Anna Słuszniak, Ryszard Mężyk and Stanisław Góźdź

Recent progress in thyroid surgery

Authors: Marek Dedecjus

The proteins of iodine metabolism in the pathophysiology of the thyroid gland

Authors: Barbara Czarnocka

Thyroid hormones – obesity and metabolic syndrome

Authors: Elżbieta Bandurska-Stankiewicz

Metabolomics provides new information on the changes occurring in thyroid tumours

Authors: Waldemar Balcerzak, S Deja, P Młynarz, A Ząbek, M Orczyk-Pawiłowicz, M Głód, T Dawiskiba and D Pawełka

The risk of malignancy of the thyroid nodule/focal lesion – an assessment by ultrasound, based on our own scoring system

Authors: Zbigniew Adamczewski and Andrzej Lewiński

Thyroid heterogeneity, as indicated by the CV of ultrasonographic intensities, correlates with anti-thyroid peroxidase antibodies in euthyroid Hashimoto’s thyroiditis

To prospectively evaluate the heterogeneous appearance of the thyroid gland, reflecting inflammation and destruction in euthyroid Hashimoto’s thyroiditis (HT), we investigated the clinical utilities of the het...

Authors: Yosuke Wakita, Toshiki Nagasaki, Yuki Nagata, Yasuo Imanishi, Shinsuke Yamada, Koichiro Yoda, Masanori Emoto, Eiji Ishimura and Masaaki Inaba

Iodine-131 induced hepatotoxicity in previously healthy patients with Grave’s disease

To describe the association of the rare and serious complication of liver toxicity in previously healthy Grave’s disease (GD) patients after the treatment with radioactive iodine ¹³¹I (RAI).

Authors: Navina Priya Jhummon, Bhavna Tohooloo and Shen Qu

Results and summary of voting among the audience during presentation and discussion of Medullary Thyroid Carcinoma clinical guidelines prepared by American Thyroid Association

The one-day ETA-CRN meeting, preceding the ETA meeting in Lisbon, was planned in advance to provide a thorough assessment of the European response to the published American Thyroid Association MTC guidelines. ...

Authors: Ulla Feldt-Rasmussen and Folke Soderstrom

Presentation of points of general discussion and voting among the speakers of the European Thyroid Association-Cancer Research Network (ETA-CRN) meeting in Lisbon, 2009, entitled ”European comments to ATA medullary thyroid cancer guidelines”

The main subjects of discussion, held online within the ETA-CRN board invited 16 expert-panelists are shown. The ad hoc emerged ETA-CRN panel of experts (EPE) first congratulated Professor Kloos and the ATA Ta...

Authors: Barbara Jarząb, Aleksandra Król, Kornelia Hasse-Lazar and Beata Jurecka-Lubieniecka

Management of hyperparathyroidism (PHP) in MEN2 syndromes in Europe

Hyperparathyroidism occurs in 20-30% of MEN2A syndrome patients. It is usually associated with mild disease and is frequently asymptomatic, especially in younger age. There is genotype/phenotype association an...

Authors: Maria Alevizaki

Timing and criteria for prophylactic thyroidectomy in asymptomatic RET carriers – the role of Ct serum level

Authors summarize in this brief review results of European discussion, held on ETA-CRN Meeting in Lisbon, 2009, on the American Thyroid Association Medullary Thyroid Cancer (MTC) Guidelines published in the sa...

Authors: Barbara Jarzab, Sylwia Szpak-Ulczok, Jan Wloch, Agnieszka Czarniecka and Jolanta Krajewska

The optimal range of RET mutations to be tested: European comments to the guidelines of the American Thyroid Association

In the 9^th ETA-CRN Meeting (September 2009, Lisbon) some recommendations from the American Thyroid Association (ATA) guidelines for the management of medullary thyroid cancer (MTC) were discussed by an European P...

Authors: Laura Fugazzola, Simone De Leo and Michela Perrino

Treatment of advanced medullary thyroid cancer

Therapy decisions in advanced medullary thyroid carcinoma should be guided by a critical appraisal of the natural disease course (slowly progressive vs. aggressive) and benefits and side effects of therapy. Th...

Authors: Johannes Smit

Clinical comments related to medullary thyroid cancer diagnosis and management

The American Thyroid Association (ATA) and more recently the European Thyroid Association (ETA) Guidelines on diagnosis and treatment of medullary thyroid carcinoma (MTC) have provided an excellent tool which ...

Authors: Leonidas H Duntas

Postoperative follow up in patients showing no evident residual disease - cut-offs for imaging/ intervention

The European Group generally agrees with the American guidelines on the issue of the indications for additional surgery in patients with recurrence of medullary thyroid cancer. The discussions have been focuse...

Authors: Michele N Minuto and Paolo Miccoli

Serum calcitonin estimation in medullary thyroid cancer: basal or stimulated levels?

Calcitonin (Ct) is a tumour marker essential for the diagnosis and follow-up of medullary thyroid cancer (MTC). Accurate and consistent measurements of serum Ct are of critical importance. Ct measurements by d...

Authors: Chantal Daumerie, Dominique Maiter and Damien Gruson

Extent of surgery in clinically evident but operable MTC – when is central and/or lateral lympadenectomy indicated?

Medullary thyroid carcinoma (MTC) metastasizes very early lymphogeneously. It has been shown that the presence of lymph node metastases is associated with a worse outcome. Postoperative biochemical cure, i.e. ...

Authors: Oliver Gimm

Calcitonin estimation in patients with nodular goiter and its significance for early detection of MTC: european comments to the guidelines of the American Thyroid Association

One of the most discussed and controversial issue in the management of thyroid nodules is the need to perform a routine measurement of serum Calcitonin (Ct) in all cases. The American Thyroid Association guide...

Authors: Rossella Elisei and Cristina Romei

Introduction to European comments on “Medullary Thyroid Cancer: management guidelines of the American Thyroid Association”

Guest Editors of Thyroid Research supplement devoted to medullary thyroid cancer present the history on how the discussion about “Medullary Thyroid Cancer: management guidelines of the American Thyroid Associatio...

Authors: Barbara Jarzab and Ulla Feldt-Rasmussen

Spectrum of lithium induced thyroid abnormalities: a current perspective

Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression and prophylaxis of bipolar disorders. Thyroid abnormalities associated with treatment with lithium have been w...

Authors: Davis Kibirige, Kenneth Luzinda and Richard Ssekitoleko

Managing thyroid dysfunction in selected special situations

Managing thyroid dysfunction is simple at first glance, the idea is to bring hormone levels in the euthyroid range, treat with antithyroid drugs, radio-iodine or surgery if toxic and replace with thyroxine or ...

Authors: Durr e Sabih and Mohammad Inayatullah

Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

The article presents a case of 57-year-old woman with the infiltration of rare small lymphocytic B cell lymphoma in the thyroid gland. Initially, the patient was followed-up due to chronic lymphocytic B-cell l...

Authors: Elżbieta Andrysiak-Mamos, Rafał Becht, Elżbieta Sowińska-Przepiera, Jakub Pobłocki, Justyna Syrenicz, Barbara Zdziarska, Katarzyna Karpińska-Kaczmarczyk and Anhelli Syrenicz

Role of metallothioneins in benign and malignant thyroid lesions

Recent findings in the past two decades have brought many insights into the biology of thyroid benign and malignant lesions, in particular the papillary and follicular thyroid cancers. Although, much progress ...

Authors: Bartosz Pula, Pawel Domoslawski, Marzena Podhorska-Okolow and Piotr Dziegiel

Oxidative damage to macromolecules in the thyroid - experimental evidence

Whereas oxidative reactions occur in all tissues and organs, the thyroid gland constitutes such an organ, in which oxidative processes are indispensable for thyroid hormone synthesis. It is estimated that huge...

Authors: Małgorzata Karbownik-Lewińska and Agnieszka Kokoszko-Bilska

High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates

The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consis...

Authors: Małgorzata Karbownik-Lewińska, Jan Stępniak and Andrzej Lewiński

Evaluation of efficacy of iodine prophylaxis in Poland based on the examination of schoolchildren living in Opoczno Town (Lodz Voivodship)

In 1997 a currently obligatory model of iodine prophylaxis, based on mandatory iodization of household salt with 30 mg KI/kg, was introduced. The aim of our study was to assess the iodine intake among school-a...

Authors: Arkadiusz Zygmunt, Zbigniew Adamczewski, Katarzyna Wojciechowska-Durczyńska, Anna Cyniak-Magierska, Kinga Krawczyk-Rusiecka, Agnieszka Zygmunt, Małgorzata Karbownik-Lewińska and Andrzej Lewiński

The role of phosphoinositide 3-kinase subunits in chronic thyroiditis

The risk of neoplastic transformation in patients with chronic thyroiditis (Hashimoto’s thyroiditis – HT) is slightly increased. Genetic background of this observation is still unclear. PI3K isoforms are linke...

Authors: Katarzyna Wojciechowska-Durczynska, Kinga Krawczyk-Rusiecka, Anna Cyniak-Magierska, Arkadiusz Zygmunt, Stanisław Sporny and Andrzej Lewinski

The influence of liver and pancreas surgery on the thyroid function

Nowadays, the increasing number of oncologic patients with liver or pancreatic tumours are subjected to surgical treatment, as it can provide a long-term survival or sometimes cure. As a result, numerous new c...

Authors: Katarzyna Wojciechowska-Durczynska, Arkadiusz Zygmunt, Adam Durczynski, Janusz Strzelczyk and Andrzej Lewinski

Prevalence of macroprolactinaemia in regularly menstruating women with non-toxic goitre or autoimmune thyroid disease

The so called “big-big” prolactin (Prl), also known as macroprolactin is formed by Prl-immunoglobulin (Prl-IgG) complexes and may cause elevation of serum Prl concentrations measured by standard assays, potent...

Authors: Krzysztof C Lewandowski, Danuta Gąsior-Perczak, Aldona Kowalska and Andrzej Lewiński