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  1. Content type: Case report

    Resistance to thyroid hormones is a very rare condition, which is often misdiagnosed and mistreated. The cases where there is a concomitant autoimmune thyroid disorder are ultra-rare and particularly challengi...

    Authors: Todor Arsov, Chengmei Xie, Nan Shen, Dan Andrews, Carola G. Vinuesa and Olivija Vaskova

    Citation: Thyroid Research 2019 12:7

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  2. Content type: Research

    Aberrant iodine intake and thyroid autoimmunity affect thyroid function. Deficiencies of iodine including thyroid disorders have serious impact on child physical and mental development. This study was conducte...

    Authors: Binaya Tamang, Saroj Khatiwada, Basanta Gelal, Shrijana Shrestha, Kishun Deo Mehta, Nirmal Baral, Gauri Shankar Shah and Madhab Lamsal

    Citation: Thyroid Research 2019 12:6

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  3. Content type: Research

    To semi-quantitatively analyze liver uptake of I-131 in diagnostic and post-therapy scans by calculating hepatic to thigh ratios (HTR) and evaluate its clinical significance in management of differentiated thy...

    Authors: Prasanta K. Pradhan, Suruchi Jain, Madhusudhanan Ponnuswamy, Amitabh Arya and Manish Ora

    Citation: Thyroid Research 2019 12:4

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  4. Content type: Research

    Thyrotoxicosis is a clinical state that results from inappropriately high thyroid hormone action in tissues. Although it is one of the common endocrine disorders, there is scarcity of data on the management of...

    Authors: Eyob Alemayehu Gebreyohannes, Emneteab Mesfin Ayele, Soliana Alemayehu Tesfaye and Mohammed Assen Seid

    Citation: Thyroid Research 2019 12:3

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  5. Content type: Review

    Both overt hypothyroidism as well as minor elevations of serum thyrotropin (TSH) levels associated with thyroid hormones within their respective reference ranges (termed subclinical hypothyroidism) are relativ...

    Authors: Owain Leng and Salman Razvi

    Citation: Thyroid Research 2019 12:2

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  6. Content type: Research

    Thyroid malignancy constitutes the sixth common cancer type in the United Arab Emirates (UAE). There are no epidemiological data outlining the prevalence of cancer in thyroid nodules, nor previous analysis of ...

    Authors: Eiman Alseddeeqi, Raqwana Baharoon, Rawia Mohamed, Jenan Ghaith, Abeer Al-Helali and Luai A. Ahmed

    Citation: Thyroid Research 2018 11:17

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  7. Content type: Research

    Nodular lesions of the thyroid gland, including papillary thyroid carcinoma (PTC), may be difficult to diagnose by imaging, such as in ultrasonic echo testing, or by needle biopsy. Definitive diagnosis is made...

    Authors: Rumi Hino, Naoko Inoshita, Toyoki Yoshimoto, Makiko Ogawa, Daishu Miura, Ryoko Watanabe, Kenta Watanabe, Mako Kamiya and Yasteru Urano

    Citation: Thyroid Research 2018 11:16

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  8. Content type: Research

    For the differential diagnosis of medullary thyroid carcinoma (MTC) on thyroid nodules, ultrasound-guided fine-needle aspiration cytology is a useful and safe procedure, but its diagnostic accuracy is not high...

    Authors: Minoru Kihara, Mitsuyoshi Hirokawa, Takumi Kudo, Toshitetsu Hayashi, Masatoshi Yamamoto, Hiroo Masuoka, Takuya Higashiyama, Mitsuhiro Fukushima, Yasuhiro Ito, Akihiro Miya and Akira Miyauchi

    Citation: Thyroid Research 2018 11:15

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  9. Content type: Research

    On 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET), diffuse uptake in the thyroid gland is often observed in patients with Hashimoto’s thyroiditis. In this study, we evaluated the factors associat...

    Authors: Naoki Edo, Koji Morita, Miki Sakamoto, Tatsuro Kaminaga, Hiromi Edo, Erina Okamura, Masumi Ogawa, Kazuhisa Tsukamoto, Hiroko Okinaga and Toshio Ishikawa

    Citation: Thyroid Research 2018 11:14

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  10. Content type: Research

    The activating mutation BRAFV600E is a frequent genetic event in papillary thyroid carcinomas (PTC). Mutation BRAFV600E is associated with the loss of a sodium/iodine symporter (NIS), and subsequent radioiodide-r...

    Authors: Honglai Zhang and Dong Chen

    Citation: Thyroid Research 2018 11:13

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  11. Content type: Case report

    Malignant biphasic tumor also known as carcinosarcoma is an uncommon neoplasm that is composed of both malignant epithelial and mesenchymal components. Most reported cases of carcinosarcoma affect the female g...

    Authors: Jing Yang, Carmen Sarita-Reyes, David Kindelberger and Qing Zhao

    Citation: Thyroid Research 2018 11:11

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  12. Content type: Case report

    Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary, histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to diagnose on clinical basis or imaging ...

    Authors: Mohamed S. Al Hassan, Tamer Saafan, Walid El Ansari, Afaf A. Al Ansari, Mahmoud A. Zirie, Hanan Farghaly and Abdelrahman Abdelaal

    Citation: Thyroid Research 2018 11:10

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  13. Content type: Research

    Iodine is important for thyroid hormone synthesis, and iodine deficiency in pregnancy may impair fetal neurological development. As perchlorate and thiocyanate inhibit sodium-iodide symporter reducing the tran...

    Authors: Bridget A. Knight, Beverley M. Shields, Xuemei He, Elizabeth N. Pearce, Lewis E. Braverman, Rachel Sturley and Bijay Vaidya

    Citation: Thyroid Research 2018 11:9

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  14. Content type: Research

    There is little information regarding the natural course of hypoechoic thyroid lesions that are probable or possible thyroid lymphoma based on fine needle aspiration cytology (FNAC) results.

    Authors: Tomoe Nakao, Mitsushige Nishikawa, Mako Hisakado, Toshihiko Kasahara, Takumi Kudo, Eijun Nishihara, Mitsuru Ito, Shuji Fukata, Hirotoshi Nakamura, Mitsuyoshi Hirokawa and Akira Miyauchi

    Citation: Thyroid Research 2018 11:8

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  15. Content type: Commentary

    Evidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results,...

    Authors: Kris Poppe, Flora Veltri and Candice Autin

    Citation: Thyroid Research 2018 11:7

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  16. Content type: Research

    Gastric ulcers are mucosal discontinuities that may extend into the mucosa, submucosa or even deeper. They result from an imbalance between mucosal aggressors and protective mechanisms that include the mucus b...

    Authors: Jackline Namulema, Miriam Nansunga, Charles Drago Kato, Muhammudu Kalange and Samuel Babafemi Olaleye

    Citation: Thyroid Research 2018 11:6

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  17. Content type: Case report

    The thyroid gland is resistant to microbial infection, because of its organ characteristics such as encapsulation, iodine content, and rich blood supply. Therefore, acute suppurative thyroiditis (AST), as a ba...

    Authors: Hazuki Otani, Masakazu Notsu, Sayo Koike, Miwa Morita, Masahiro Yamamoto, Mika Yamauchi, Takahumi Fuchiwaki, Ichiro Morikura, Noriaki Aoi, Hideyuki Kawauchi, Teruaki Iwabashi, Asuka Araki, Noriyoshi Ishikawa, Riruke Maruyama and Toshitsugu Sugimoto

    Citation: Thyroid Research 2018 11:4

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  18. Content type: Research

    We aimed to study the validity of six published ultrasound criteria for risk stratification of thyroid nodules in the former severely iodine deficient population of Austria.

    Authors: Christina Tugendsam, Veronika Petz, Wolfgang Buchinger, Brigitta Schmoll-Hauer, Iris Pia Schenk, Karin Rudolph, Michael Krebs and Georg Zettinig

    Citation: Thyroid Research 2018 11:3

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  19. Content type: Short report

    Autoimmune thyroid disorders (AITD) broadly include Graves’ disease and Hashimoto’s thyroiditis which are the most common causes of thyroid gland dysfunctions. These disorders develop due to complex interactio...

    Authors: Marta Rydzewska, Michał Jaromin, Izabela Elżbieta Pasierowska, Karlina Stożek and Artur Bossowski

    Citation: Thyroid Research 2018 11:2

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  20. Content type: Review

    Whilst trials of combination levothyroxine/liothyronine therapy versus levothyroxine monotherapy for thyroid hormone replacement have not shown any superiority, there remains a small subset of patients who do ...

    Authors: Colin Dayan and Vijay Panicker

    Citation: Thyroid Research 2018 11:1

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  21. Content type: Case report

    Recurrent papillary thyroid carcinoma (PTC) beyond the first two decades of definitive treatment (i.e. total thyroidectomy and radioactive iodine ablation) is a rare occurrence.

    Authors: Yaw Amoako-Tuffour, M. Elise Graham, Martin Bullock, Matthew H. Rigby, Jonathan Trites, S. Mark Taylor and Robert D. Hart

    Citation: Thyroid Research 2017 10:8

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  22. Content type: Case report

    Hyalinizing trabecular tumors (HTT) are rare follicular cell-derived tumors of the thyroid gland that are infrequently reported in otolaryngology literature. We present here an interesting case of HTT which pr...

    Authors: Dustin J. Jones, Christopher R. Kieliszak, Sanjay S. Patel and Christopher R. Selinsky

    Citation: Thyroid Research 2017 10:7

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  23. Content type: Research

    Medullary thyroid carcinoma (MTC) accounts for 1-2% of all thyroid cancers. The clinical course of metastatic disease can be indolent. Our aim was to characterize the natural history of disease to evaluate the...

    Authors: Georgia Geller, Janessa Laskin, Winson Y. Cheung and Cheryl Ho

    Citation: Thyroid Research 2017 10:6

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  24. Content type: Research

    Pregnancy and delivery markedly influence thyroid function. However, the comparative prevalence of gestational thyrotoxicosis (GT), new onset of Graves’ disease during pregnancy (GD during pregnancy), postpart...

    Authors: Akane Ide, Nobuyuki Amino, Takumi Kudo, Waka Yoshioka, Mako Hisakado, Eijun Nishihara, Mitsuru Ito, Shuji Fukata, Hirotoshi Nakamura and Akira Miyauchi

    Citation: Thyroid Research 2017 10:4

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  25. Content type: Case report

    Struma ovarii is a rare monodermal germ cell tumor where the ovary is comprised of at least half thyroid tissue. This phenomenon may indicate an embryological origin.

    Authors: J. Colin Boyd, Blair A. Williams, Matthew H. Rigby, Katharina Kieser, Saul Offman, Hemlata Shirsat, Jonathan R. B. Trites, S. Mark Taylor and Robert D. Hart

    Citation: Thyroid Research 2017 10:3

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  26. Content type: Meeting abstracts

    Authors: Luigi Bartalena, Eric Fliers, Nicola Hellen, Peter N. Taylor, Arron Lacey, Daniel Thayer, Mohd Draman Yusof, Arshiya Tabasum, Illaria Muller, Luke Marsh, Marian Ludgate, Alex Rees, Kristien Boelaert, Shiao Chan, Scott Nelson, Aled Rees…

    Citation: Thyroid Research 2017 10(Suppl 1):2

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    This article is part of a Supplement: Volume 10 Supplement 1

  27. Content type: Proceedings

    Authors: Leonard Wartofsky, Peter Smyth, Josef Köhrle, Ryszard Anielski, Marian Slowiaczek, Pawel Orlicki, Rafal Czepczynski, Jacek Daroszewski, Alicja Hubalewska-Dydejczyk, Aldona Kowalska, Maria Kurowska, Joanna Malicka, Anna Oszywa-Chabros, Agnieszka Zwolak, Jerzy S. Tarach, Krzysztof C. Lewandowski…

    Citation: Thyroid Research 2016 9(Suppl 1):6

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    This article is part of a Supplement: Volume 9 Supplement 1

  28. Content type: Research

    Hypothyroidism is a common condition, particularly in the older population. Thyroid hormone requirements change with age and serum TSH levels also alter, especially in older patients. However, in practice labo...

    Authors: Salman Razvi, Lorna Ingoe, Vicky Ryan, Simon H. S. Pearce and Scott Wilkes

    Citation: Thyroid Research 2016 9:5

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  29. Content type: Research

    Although the majority of thyroid nodules are benign the process of excluding malignancy is challenging and sometimes involves unnecessary surgical procedures. We explored the development of a predictive model ...

    Authors: Justyna Witczak, Peter Taylor, Jason Chai, Bethan Amphlett, Jean-Marc Soukias, Gautam Das, Brian P. Tennant, John Geen and Onyebuchi E. Okosieme

    Citation: Thyroid Research 2016 9:4

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  30. Content type: Editorial

    It is eight years since Thyroid Research was launched with an aim to enhance opportunities for scientists and clinicians, working in the rapidly advancing field of thyroidology, to publish their research (Thyroid...

    Authors: Bijay Vaidya and Andrzej Lewinski

    Citation: Thyroid Research 2016 9:3

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  31. Content type: Case report

    A change in a thyrometabolic state from severe hypothyroidism to thyrotoxicosis is very uncommon, but possible in some circumstances.

    Authors: Krzysztof Lewandowski, Katarzyna Dąbrowska, Jacek Makarewicz and Andrzej Lewiński

    Citation: Thyroid Research 2016 9:1

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  32. Content type: Case report

    Though compliance (or adherence) problems, as well as inappropriate levothyroxine (L-T4) intake (e.g. with meal, other drugs or certain foods that can significantly affect absorption) are very common, the issue i...

    Authors: Krzysztof C. Lewandowski, Katarzyna Dąbrowska, Iwona Komorowska-Dudek and Andrzej Lewiński

    Citation: Thyroid Research 2015 8:16

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  33. Content type: Review

    Several meta-analyses have been performed comparing the use of a variety of ultrasonic devices in thyroidectomy to conventional procedures. These studies have shown the superiority of ultrasonic devices for mo...

    Authors: Hang Cheng, Ireena Soleas, Nicole C. Ferko, Jeffrey W. Clymer and Joseph F. Amaral

    Citation: Thyroid Research 2015 8:15

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  34. Content type: Research

    Medullary thyroid cancer (MTC) is a C-cell neoplasm. Surgery remains its main treatment. Promising therapies based on tyrosine kinase inhibitors demand careful patient selection. We previously observed that tw...

    Authors: Thierry Ragot, Claire Provost, Aurélie Prignon, Régis Cohen, Michel Lepoivre and Sylvie Lausson

    Citation: Thyroid Research 2015 8:13

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  35. Content type: Research

    Thyroperoxidase (TPO) is a membrane-bound protein essential for the production of thyroid hormones; because of this, TPO expression may be impaired in selected thyroid diseases. The goal of this study is to an...

    Authors: Yurena Caballero, Eudaldo M. López-Tomassetti, Julián Favre, José R. Santana, Juan J. Cabrera and Juan R. Hernández

    Citation: Thyroid Research 2015 8:12

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  36. Content type: Short report

    Circulating thyrotropin receptor messenger ribonucleic acid (TSHR mRNA) assay has been validated in the follow-up of differentiated thyroid carcinoma (DTC) because of its high sensitivity during thyroid hormon...

    Authors: Surasawadee Ausavarat, Jiraporn Sriprapaporn, Busara Satayaban, Wanna Thongnoppakhun, Aunchalee Laipiriyakun, Boontham Amornkitticharoen, Rujaporn Chanachai and Chaveevan Pattanachak

    Citation: Thyroid Research 2015 8:11

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  37. Content type: Research

    The ratio of serum free triiodothyronine (FT3) to free thyroxine (FT4) has been shown to be constant in healthy adults. However, this ratio has been found to be decreased in athyreotic adult patients on levoth...

    Authors: Yuji Oto, Koji Muroya, Junko Hanakawa, Yumi Asakura and Masanori Adachi

    Citation: Thyroid Research 2015 8:10

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  38. Content type: Short report

    Stroke is the fifth leading cause of death and the primary cause of long-term adult disability in the United States. Increasing evidence suggests that low T3 levels immediately following acute ischemic stroke ...

    Authors: Lena M. O’Keefe, Sarah E. Conway, Alexandra Czap, Carl D. Malchoff, Sharon Benashski, Gilbert Fortunato, Ilene Staff and Louise D. McCullough

    Citation: Thyroid Research 2015 8:9

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